ERCC1 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/3/3b/Protein_ERCC1_PDB_1z00.png/250px-Protein_ERCC1_PDB_1z00.png) |
Estructures disponibles |
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PDB | Cerca ortòloga: PDBe RCSB |
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Llista de codis id de PDB |
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1Z00, 2A1I, 2A1J, 2JNW, 2JPD, 2MUT |
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Identificadors |
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Àlies | ERCC1, COFS4, RAD10, UV20, excision repair cross-complementation group 1, ERCC excision repair 1, endonuclease non-catalytic subunit |
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IDs externes | OMIM: 126380 MGI: 95412 HomoloGene: 1501 GeneCards: ERCC1 OMA: ERCC1 - orthologs |
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Localització del gen (humà) |
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![Cromosoma 19 (humà)](//upload.wikimedia.org/wikipedia/commons/thumb/5/54/Ideogram_human_chromosome_19.svg/300px-Ideogram_human_chromosome_19.svg.png) | Crom. | Cromosoma 19 (humà)[1] |
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| Banda | 19q13.32 | Inici | 45.407.333 bp[1] |
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Fi | 45.478.828 bp[1] |
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Localització del gen (ratolí) |
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![Cromosoma 7 (ratolí)](//upload.wikimedia.org/wikipedia/commons/thumb/e/e4/Ideogram_house_mouse_chromosome_7.svg/260px-Ideogram_house_mouse_chromosome_7.svg.png) | Crom. | Cromosoma 7 (ratolí)[2] |
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| Banda | 7 A3|7 9.6 cM | Inici | 19.078.703 bp[2] |
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Fi | 19.090.449 bp[2] |
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Patró d'expressió d'ARN |
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Bgee | Humà | Ratolí (ortòleg) |
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Més explicacions | - apex of heart
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png)
- paròtide
- right auricle
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png)
- ventricle esquerre
- eminència ganglionar
![Podeu corregir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/3/32/OOjs_UI_icon_Wikidata_Echo_lightcolors.svg/10px-OOjs_UI_icon_Wikidata_Echo_lightcolors.svg.png)
- left ovary
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png)
- ventricular zone
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png)
- muscle of thigh
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png)
- right ovary
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png)
- stromal cell of endometrium
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png)
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| | Més dades d'expressió de referència |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/5/56/PBB_GE_ERCC1_203720_s_at_fs.png/250px-PBB_GE_ERCC1_203720_s_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/e/e1/PBB_GE_ERCC1_203719_at_fs.png/250px-PBB_GE_ERCC1_203719_at_fs.png) | Més referències a dades d'expressió |
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Ontologia genètica |
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Funció molecular | - protein domain specific binding
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - single-stranded DNA binding
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - damaged DNA binding
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - single-stranded DNA endodeoxyribonuclease activity
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - protein C-terminus binding
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - unió proteica
![](//upload.wikimedia.org/wikipedia/commons/thumb/f/f6/Wiki_article_small_light.svg/10px-Wiki_article_small_light.svg.png) - TFIID-class transcription factor complex binding
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - nuclease activity
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - endonuclease activity
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - activitat hidrolasa
![Podeu corregir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/3/32/OOjs_UI_icon_Wikidata_Echo_lightcolors.svg/10px-OOjs_UI_icon_Wikidata_Echo_lightcolors.svg.png) - 3' overhang single-stranded DNA endodeoxyribonuclease activity
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - DNA binding
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) | Component cel·lular | - ERCC4-ERCC1 complex
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - transcription factor TFIID complex
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - nucleoplasma
![](//upload.wikimedia.org/wikipedia/commons/thumb/f/f6/Wiki_article_small_light.svg/10px-Wiki_article_small_light.svg.png) - nucleotide-excision repair factor 1 complex
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - nucleotide-excision repair complex
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - nucli cel·lular
![](//upload.wikimedia.org/wikipedia/commons/thumb/f/f6/Wiki_article_small_light.svg/10px-Wiki_article_small_light.svg.png) - citoplasma
![](//upload.wikimedia.org/wikipedia/commons/thumb/f/f6/Wiki_article_small_light.svg/10px-Wiki_article_small_light.svg.png) - citosol
![](//upload.wikimedia.org/wikipedia/commons/thumb/f/f6/Wiki_article_small_light.svg/10px-Wiki_article_small_light.svg.png) | Procés biològic | - germ cell development
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - DNA recombination
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - male gonad development
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - interstrand cross-link repair
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - positive regulation of t-circle formation
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - cell development
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - response to nutrient
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - multicellular organism growth
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - embryonic organ development
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - post-embryonic hemopoiesis
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - syncytium formation
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - response to oxidative stress
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - chromosome organization
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - pyrimidine dimer repair by nucleotide-excision repair
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - ovogènesi
![](//upload.wikimedia.org/wikipedia/commons/thumb/f/f6/Wiki_article_small_light.svg/10px-Wiki_article_small_light.svg.png) - cellular response to DNA damage stimulus
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - global genome nucleotide-excision repair
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - canvi de classe d'immunoglobulina
![](//upload.wikimedia.org/wikipedia/commons/thumb/f/f6/Wiki_article_small_light.svg/10px-Wiki_article_small_light.svg.png) - espermatogènesi
![](//upload.wikimedia.org/wikipedia/commons/thumb/f/f6/Wiki_article_small_light.svg/10px-Wiki_article_small_light.svg.png) - multicellular organism aging
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - UV protection
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - t-circle formation
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - negative regulation of telomere maintenance
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - transcription-coupled nucleotide-excision repair
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - mitotic recombination
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - proliferació cel·lular
![](//upload.wikimedia.org/wikipedia/commons/thumb/f/f6/Wiki_article_small_light.svg/10px-Wiki_article_small_light.svg.png) - nucleotide-excision repair, DNA incision
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - response to X-ray
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - response to sucrose
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - Reparació per excisió de nucleòtid
![](//upload.wikimedia.org/wikipedia/commons/thumb/f/f6/Wiki_article_small_light.svg/10px-Wiki_article_small_light.svg.png) - nucleotide-excision repair, preincision complex stabilization
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - double-strand break repair
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - reparació de l'ADN
![](//upload.wikimedia.org/wikipedia/commons/thumb/f/f6/Wiki_article_small_light.svg/10px-Wiki_article_small_light.svg.png) - nucleotide-excision repair, DNA incision, 5'-to lesion
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - nucleotide-excision repair, DNA incision, 3'-to lesion
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - meiotic mismatch repair
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - double-strand break repair via nonhomologous end joining
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - UV-damage excision repair
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - negative regulation of protection from non-homologous end joining at telomere
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - telomeric DNA-containing double minutes formation
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - response to immobilization stress
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - response to cadmium ion
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) - nucleic acid phosphodiester bond hydrolysis
![Podeu traduir-lo](//upload.wikimedia.org/wikipedia/commons/thumb/4/46/OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg/17px-OOjs_UI_icon_Wikidata_Echo_lightcolors_en.svg.png) | Fonts:Amigo / QuickGO |
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Ortòlegs |
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Espècies | Humà | Ratolí |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (ARNm) | |
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NM_001166049 NM_001983 NM_202001 |
| |
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RefSeq (proteïna) | NP_001159521 NP_001974 NP_973730 NP_001356337 NP_001356338
|
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NP_001356339 NP_001356340 NP_001356341 NP_001356342 NP_001356343 NP_001356344 NP_001356345 NP_001356346 NP_001356347 NP_001356348 |
| |
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Localització (UCSC) | Chr 19: 45.41 – 45.48 Mb | Chr 7: 19.08 – 19.09 Mb |
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Cerca a PubMed | [3] | [4] |
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Wikidata |
Veure/Editar Humà | Veure/Editar Ratolí |
|