5-aminopentanamidase

In enzymology, a 5-aminopentanamidase (EC 3.5.1.30) is an enzyme that catalyzes the chemical reaction

5-aminopentanamide + H₂O ${\displaystyle \rightleftharpoons }$ 5-aminopentanoate + NH₃

Thus, the two substrates of this enzyme are 5-aminopentanamide and H₂O, whereas its two products are 5-aminopentanoate and NH₃.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is 5-aminopentanamide amidohydrolase. Other names in common use include 5-aminovaleramidase, and 5-aminonorvaleramidase. This enzyme participates in lysine degradation.

• Reitz MS, Rodwell VW (1970). "Delta-aminovaleramidase of Pseudomonas putida". J. Biol. Chem. 245 (12): 3091–6. PMID 5432799.
• Takeda H, Yamamoto S, Kojima Y, Hayaishi O (1969). "Studies on monooxygenases. I. General properties of crystalline L-lysine monooxygenase". J. Biol. Chem. 244 (11): 2935–41. PMID 5772467.