ADAMTS12 |
---|
|
Identifiers |
---|
Aliases | ADAMTS12, PRO4389, ADAM metallopeptidase with thrombospondin type 1 motif 12 |
---|
External IDs | OMIM: 606184; MGI: 2146046; HomoloGene: 12808; GeneCards: ADAMTS12; OMA:ADAMTS12 - orthologs |
---|
Gene location (Human) |
---|
| Chr. | Chromosome 5 (human)[1] |
---|
| Band | 5p13.3-p13.2 | Start | 33,523,535 bp[1] |
---|
End | 33,892,019 bp[1] |
---|
|
Gene location (Mouse) |
---|
| Chr. | Chromosome 15 (mouse)[2] |
---|
| Band | 15|15 A1 | Start | 11,064,790 bp[2] |
---|
End | 11,349,231 bp[2] |
---|
|
RNA expression pattern |
---|
Bgee | Human | Mouse (ortholog) |
---|
Top expressed in | - testicle
- stromal cell of endometrium
- visceral pleura
- gonad
- islet of Langerhans
- adipose tissue
- subcutaneous adipose tissue
- sural nerve
- abdominal fat
- parietal pleura
|
| Top expressed in | - dermis
- stroma of bone marrow
- calvaria
- efferent ductule
- vestibular sensory epithelium
- mammary gland
- external carotid artery
- aortic valve
- internal carotid artery
- otolith organ
|
| More reference expression data |
|
---|
BioGPS | | More reference expression data |
|
---|
|
Gene ontology |
---|
Molecular function | - metal ion binding
- peptidase activity
- protein binding
- metalloendopeptidase activity
- hydrolase activity
- metallopeptidase activity
- zinc ion binding
| Cellular component | - extracellular region
- extracellular matrix
- collagen-containing extracellular matrix
| Biological process | - regulation of endothelial tube morphogenesis
- proteoglycan catabolic process
- negative regulation of hepatocyte growth factor receptor signaling pathway
- negative regulation of cellular response to vascular endothelial growth factor stimulus
- cellular response to tumor necrosis factor
- cellular response to BMP stimulus
- negative regulation of cellular response to hepatocyte growth factor stimulus
- proteolysis
- negative regulation of chondrocyte differentiation
- cellular response to interleukin-1
- regulation of inflammatory response
- proteolysis involved in cellular protein catabolic process
- cell-matrix adhesion
- cell migration
| Sources:Amigo / QuickGO |
|
Orthologs |
---|
Species | Human | Mouse |
---|
Entrez | | |
---|
Ensembl | |
---|
ENSG00000151388 ENSG00000281690 |
| |
---|
UniProt | | |
---|
RefSeq (mRNA) | |
---|
NM_030955 NM_001324511 NM_001324512 |
| |
---|
RefSeq (protein) | |
---|
NP_001311440 NP_001311441 NP_112217 |
| |
---|
Location (UCSC) | Chr 5: 33.52 – 33.89 Mb | Chr 15: 11.06 – 11.35 Mb |
---|
PubMed search | [3] | [4] |
---|
|
Wikidata |
View/Edit Human | View/Edit Mouse |
|