ARHGAP44 |
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Identifiers |
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Aliases | ARHGAP44, NPC-A-10, RICH2, Rho GTPase activating protein 44 |
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External IDs | OMIM: 617716; MGI: 2144423; HomoloGene: 65284; GeneCards: ARHGAP44; OMA:ARHGAP44 - orthologs |
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Gene location (Human) |
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![Chromosome 17 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/0/00/Ideogram_human_chromosome_17.svg/300px-Ideogram_human_chromosome_17.svg.png) | Chr. | Chromosome 17 (human)[1] |
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| Band | 17p12 | Start | 12,789,498 bp[1] |
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End | 12,991,643 bp[1] |
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Gene location (Mouse) |
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![Chromosome 11 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/a/a5/Ideogram_house_mouse_chromosome_11.svg/260px-Ideogram_house_mouse_chromosome_11.svg.png) | Chr. | Chromosome 11 (mouse)[2] |
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| Band | 11|11 B3 | Start | 64,892,865 bp[2] |
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End | 65,053,787 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - lateral nuclear group of thalamus
- Brodmann area 23
- middle temporal gyrus
- buccal mucosa cell
- germinal epithelium
- primary visual cortex
- cerebellar cortex
- cerebellar hemisphere
- prefrontal cortex
- right hemisphere of cerebellum
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| Top expressed in | - medial vestibular nucleus
- pontine nuclei
- deep cerebellar nuclei
- substantia nigra
- medial dorsal nucleus
- medial geniculate nucleus
- lateral geniculate nucleus
- dorsal tegmental nucleus
- piriform cortex
- primary motor cortex
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - protein binding
- phospholipid binding
- GTPase activator activity
| Cellular component | - cytoplasm
- recycling endosome
- cytosol
- cell junction
- endosome
- dendritic spine
- cell projection
- synapse
- leading edge membrane
- glutamatergic synapse
- intracellular anatomical structure
- postsynaptic density
- presynaptic active zone
| Biological process | - positive regulation of GTPase activity
- regulation of small GTPase mediated signal transduction
- signal transduction
- exocytosis
- regulation of actin cytoskeleton organization
- regulation of GTPase activity
- regulation of dendritic spine morphogenesis
- modification of dendritic spine
- neurotransmitter receptor transport, endosome to postsynaptic membrane
- negative regulation of Rac protein signal transduction
- modification of postsynaptic structure
- regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_014859 NM_001321164 NM_001321166 NM_001321167 NM_001321168 |
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RefSeq (protein) | |
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NP_001308093 NP_001308095 NP_001308096 NP_001308097 NP_055674 |
| NP_001092758 NP_778168 NP_001395152 NP_001395153 NP_001395155
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NP_001395157 |
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Location (UCSC) | Chr 17: 12.79 – 12.99 Mb | Chr 11: 64.89 – 65.05 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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