Azosemide
Chemical compound
- none
- 2-chloro-5-(2H-tetrazol-5-yl)-4-[(thiophen-2-ylmethyl)amino]benzenesulfonamide
- 27589-33-9 N
- 2273
- DB08961 N
- 2186 Y
- MR40VT1L8Z
- D01323 Y
- CHEBI:31248 Y
- ChEMBL1097235 Y
- DTXSID7046910
- Interactive image
- O=S(=O)(N)c2c(Cl)cc(c(c1n[nH]nn1)c2)NCc3sccc3
InChI
- InChI=1S/C12H11ClN6O2S2/c13-9-5-10(15-6-7-2-1-3-22-7)8(12-16-18-19-17-12)4-11(9)23(14,20)21/h1-5,15H,6H2,(H2,14,20,21)(H,16,17,18,19) Y
- Key:HMEDEBAJARCKCT-UHFFFAOYSA-N Y
Azosemide is a high-ceiling loop diuretic agent that was brought to market in 1981 by Boehringer Mannheim.[1][2] As of 2015 it was available as a generic in some Asian countries.[3]
Azosemide has been found as an adulterant in ketamine.[4]
References
- ^ Sittig M (1988). Pharmaceutical Manufacturing Encyclopedia (PDF). Vol. 1. Noyes Publications. p. 122. ISBN 978-0-8155-1144-1. Archived from the original (PDF) on 2007-10-23.
- ^ Bormann D (January 1980). "Diuretics". In Hess HJ (ed.). Annual Reports in Medicinal Chemistry. Vol. 15. Academic Press. pp. 100–105 (101). ISBN 978-0-08-058359-4.
- ^ "International listings for azosemide". Drugs.com. Retrieved 23 July 2015.
- ^ "Drug Checking Report 2011" (PDF). Energy Control. Retrieved 20 January 2022.
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Diuretics (C03)
(and etacrynic acid)
CA inhibitors (at PT) | |
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Loop (Na-K-Cl at AL) | |
Thiazides (Na-Cl at DCT, Calcium-sparing) | |
Thiazide-likes (primarily DCT) |
ESC blockers | |
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Aldosterone antagonists |
(DCT and CD)
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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