CD99L2

Protein-coding gene in humans
CD99L2
Identifiers
AliasesCD99L2, CD99B, MIC2L1, CD99 molecule like 2
External IDsOMIM: 300846; MGI: 2177151; HomoloGene: 135743; GeneCards: CD99L2; OMA:CD99L2 - orthologs
Gene location (Human)
X chromosome (human)
Chr.X chromosome (human)[1]
X chromosome (human)
Genomic location for CD99L2
Genomic location for CD99L2
BandXq28Start150,766,336 bp[1]
End150,898,816 bp[1]
Gene location (Mouse)
X chromosome (mouse)
Chr.X chromosome (mouse)[2]
X chromosome (mouse)
Genomic location for CD99L2
Genomic location for CD99L2
BandX|X A7.3Start70,463,666 bp[2]
End70,536,455 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • prefrontal cortex

  • gastrocnemius muscle

  • right frontal lobe

  • lateral nuclear group of thalamus

  • Brodmann area 9

  • C1 segment

  • muscle of thigh

  • hypothalamus

  • cingulate gyrus

  • anterior cingulate cortex
Top expressed in
  • Rostral migratory stream

  • facial motor nucleus

  • muscle of thigh

  • ciliary body

  • iris

  • retinal pigment epithelium

  • masseter muscle

  • pontine nuclei

  • ventromedial nucleus

  • aortic valve
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • protein binding
Cellular component
  • integral component of membrane
  • cell junction
  • plasma membrane
  • membrane
  • focal adhesion
  • cell surface
  • integral component of plasma membrane
Biological process
  • cell adhesion
  • diapedesis
  • positive regulation of neutrophil extravasation
  • positive regulation of T cell extravasation
  • homotypic cell-cell adhesion
  • T cell extravasation
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

83692

171486

Ensembl

ENSG00000102181

ENSMUSG00000035776

UniProt

Q8TCZ2

Q8BIF0

RefSeq (mRNA)

NM_001184808
NM_001242614
NM_031462
NM_134445
NM_134446

NM_001199349
NM_138309

RefSeq (protein)

NP_001171737
NP_001229543
NP_113650
NP_604394
NP_604395

NP_001186278
NP_612182

Location (UCSC)Chr X: 150.77 – 150.9 MbChr X: 70.46 – 70.54 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

CD99 antigen-like protein 2 is a protein that in humans is encoded by the CD99L2 gene.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000102181 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000035776 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: CD99L2 CD99 molecule-like 2".

Further reading

  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
  • Suh YH, Shin YK, Kook MC, et al. (2003). "Cloning, genomic organization, alternative transcripts and expression analysis of CD99L2, a novel paralog of human CD99, and identification of evolutionary conserved motifs". Gene. 307: 63–76. doi:10.1016/S0378-1119(03)00401-3. PMID 12706889.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.


  • v
  • t
  • e