Ciclobendazole
Chemical compound
- P02CA04 (WHO)
- Methyl N-[6-(cyclopropanecarbonyl)-1H-benzimidazol-2-yl]carbamate
- 31431-43-3
Y
- 35803
- 32933
N
- JF3KQ40J31
- D03623
Y
- DTXSID9057713
![Edit this at Wikidata](http://upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png)
- Interactive image
- COC(=O)Nc3nc2ccc(C(=O)C1CC1)cc2[nH]3
InChI
- InChI=1S/C13H13N3O3/c1-19-13(18)16-12-14-9-5-4-8(6-10(9)15-12)11(17)7-2-3-7/h4-7H,2-3H2,1H3,(H2,14,15,16,18)
N
- Key:OXLKOMYHDYVIDM-UHFFFAOYSA-N
N
![☒](http://upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/7px-X_mark.svg.png)
![check](http://upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png)
Ciclobendazole is an anthelmintic, that is a pharmaceutical drug against parasitic worms. It underwent a clinical trial in the 1970s, where it was found to be as effective as mebendazole in the treatment of hookworm infection and ascariasis, but significantly less effective in the treatment of trichuriasis.[1]
It is not known to be marketed anywhere in the world.[2]
References
- ^ Guggenmoos R, Akhtaruzzaman KM, Rosenkaimer F, Gaus W, Bienzle U, Dietrich M (December 1978). "Comparative trial on the therapeutic effectiveness of the new anthelmintic drug: ciclobendazole". Tropenmedizin und Parasitologie. 29 (4): 423–6. PMID 369076.
- ^ "Ciclobendazole search results". Drugs.com. Retrieved 2021-03-31.
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Antitrematodals (schistosomicides) |
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Anticestodals (taeniacides) |
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(including
macrofilaricides)
Binds tubulin |
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Glutamate-gated chloride channel, GABA receptor | |
NMDA |
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Other/unknown |
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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