COL1A2 |
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Identifiers |
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Aliases | COL1A2, OI4, collagen type I alpha 2, collagen type I alpha 2 chain, EDSCV, EDSARTH2 |
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External IDs | OMIM: 120160; MGI: 88468; HomoloGene: 69; GeneCards: COL1A2; OMA:COL1A2 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 7 (human)[1] |
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| Band | 7q21.3 | Start | 94,394,895 bp[1] |
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End | 94,431,227 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 6 (mouse)[2] |
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| Band | 6 A1|6 1.81 cM | Start | 4,504,814 bp[2] |
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End | 4,541,544 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - periodontal fiber
- stromal cell of endometrium
- skin of hip
- tibia
- visceral pleura
- parietal pleura
- saphenous vein
- tendon of biceps brachii
- gallbladder
- skin of thigh
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| Top expressed in | - calvaria
- body of femur
- efferent ductule
- tibiofemoral joint
- ascending aorta
- fossa
- vas deferens
- aortic valve
- belly cord
- stroma of bone marrow
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| More reference expression data |
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BioGPS |
| More reference expression data |
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Gene ontology |
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Molecular function | - metal ion binding
- identical protein binding
- SMAD binding
- protein-macromolecule adaptor activity
- platelet-derived growth factor binding
- extracellular matrix structural constituent
- protein binding
- protease binding
- extracellular matrix structural constituent conferring tensile strength
| Cellular component | - extracellular exosome
- endoplasmic reticulum lumen
- extracellular matrix
- collagen
- collagen type I trimer
- extracellular space
- endoplasmic reticulum
- extracellular region
- collagen-containing extracellular matrix
| Biological process | - blood coagulation
- transforming growth factor beta receptor signaling pathway
- extracellular matrix organization
- collagen fibril organization
- skin morphogenesis
- odontogenesis
- skeletal system development
- collagen catabolic process
- regulation of blood pressure
- blood vessel development
- regulation of immune response
- leukocyte migration
- protein heterotrimerization
- cellular response to amino acid stimulus
- platelet activation
- Rho protein signal transduction
- cytokine-mediated signaling pathway
- bone mineralization
- collagen metabolic process
- extracellular matrix assembly
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 7: 94.39 – 94.43 Mb | Chr 6: 4.5 – 4.54 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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