FNDC3A

Protein-coding gene in the species Homo sapiens
FNDC3A
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

1WK0, 1X3D, 1X4X, 1X5X, 2CRM, 2CRZ

Identifiers
AliasesFNDC3A, FNDC3, HUGO, bA203I16.1, bA203I16.5, fibronectin type III domain containing 3A
External IDsOMIM: 615794; MGI: 1196463; HomoloGene: 8952; GeneCards: FNDC3A; OMA:FNDC3A - orthologs
Gene location (Human)
Chromosome 13 (human)
Chr.Chromosome 13 (human)[1]
Chromosome 13 (human)
Genomic location for FNDC3A
Genomic location for FNDC3A
Band13q14.2Start48,975,912 bp[1]
End49,209,779 bp[1]
Gene location (Mouse)
Chromosome 14 (mouse)
Chr.Chromosome 14 (mouse)[2]
Chromosome 14 (mouse)
Genomic location for FNDC3A
Genomic location for FNDC3A
Band14 D2|14 37.62 cMStart72,775,386 bp[2]
End72,947,443 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • corpus epididymis

  • caput epididymis

  • jejunal mucosa

  • cardia

  • tail of epididymis

  • germinal epithelium

  • decidua

  • islet of Langerhans

  • mucosa of paranasal sinus

  • body of pancreas
Top expressed in
  • parotid gland

  • decidua

  • seminal vesicula

  • median eminence

  • lacrimal gland

  • submandibular gland

  • arcuate nucleus

  • gastrula

  • islet of Langerhans

  • pineal gland
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • RNA binding
Cellular component
  • integral component of membrane
  • cytosol
  • Golgi membrane
  • Golgi apparatus
  • acrosomal vesicle
  • membrane
  • cytoplasmic vesicle
  • vesicle membrane
Biological process
  • fertilization
  • Sertoli cell development
  • spermatid development
  • cell-cell adhesion
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

22862

319448

Ensembl

ENSG00000102531

ENSMUSG00000033487

UniProt

Q9Y2H6

Q8BX90

RefSeq (mRNA)

NM_001079673
NM_001278438
NM_014923

NM_207636

RefSeq (protein)

NP_001073141
NP_001265367
NP_055738

NP_997519

Location (UCSC)Chr 13: 48.98 – 49.21 MbChr 14: 72.78 – 72.95 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Fibronectin type-III domain-containing protein 3a is a protein that in humans is encoded by the FNDC3A gene.[5]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000102531 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000033487 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: FNDC3A fibronectin type III domain containing 3A".

Further reading

  • Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
  • Carrouel F, Couble ML, Vanbelle C, et al. (2008). "HUGO (FNDC3A): a new gene overexpressed in human odontoblasts". J. Dent. Res. 87 (2): 131–6. doi:10.1177/154405910808700209. PMID 18218838. S2CID 27513925.
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13". Nature. 428 (6982): 522–8. Bibcode:2004Natur.428..522D. doi:10.1038/nature02379. PMC 2665288. PMID 15057823.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (1): 63–70. doi:10.1093/dnares/6.1.63. PMID 10231032.
  • Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
  • v
  • t
  • e
  • 1wk0: Solution structure of Fibronectin type III domain derived from human KIAA0970 protein
    1wk0: Solution structure of Fibronectin type III domain derived from human KIAA0970 protein
  • 1x3d: Solution structure of the fibronectin type-III domain of human fibronectin type-III domain containing protein 3a
    1x3d: Solution structure of the fibronectin type-III domain of human fibronectin type-III domain containing protein 3a
  • 1x4x: Solution structure of the 6th fibronectin type III domain from human fibronectin type III domain containing protein 3
    1x4x: Solution structure of the 6th fibronectin type III domain from human fibronectin type III domain containing protein 3
  • 1x5x: Solution structure of the fibronectin type-III domain of human fibronectin type III domain containing protein 3
    1x5x: Solution structure of the fibronectin type-III domain of human fibronectin type III domain containing protein 3
  • 2crm: Solution structure of the fourth FNIII domain of human
    2crm: Solution structure of the fourth FNIII domain of human
  • 2crz: Solution structure of the fifth FNIII domain of human fibronectin type III domain containing protein 3a
    2crz: Solution structure of the fifth FNIII domain of human fibronectin type III domain containing protein 3a


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