Fanetizole

Chemical compound
Fanetizole
Pharmacokinetic data
Protein binding%
Identifiers
  • 4-Phenyl-N-(2-phenylethyl)-1,3-thiazol-2-amine
CAS Number
  • 79069-94-6
PubChem CID
  • 54339
ChemSpider
  • 49083
UNII
  • BH48F620JA
CompTox Dashboard (EPA)
  • DTXSID9048695 Edit this at Wikidata
Chemical and physical data
FormulaC17H16N2S
Molar mass280.39 g·mol−1
3D model (JSmol)
  • Interactive image
  • n1c(csc1NCCc2ccccc2)c3ccccc3
InChI
  • InChI=1S/C17H16N2S/c1-3-7-14(8-4-1)11-12-18-17-19-16(13-20-17)15-9-5-2-6-10-15/h1-10,13H,11-12H2,(H,18,19)
  • Key:WEEYMMXMBFJUAI-UHFFFAOYSA-N
  (verify)

Fanetizole is a drug that has immunoregulating activity.[citation needed]

Synthesis

Reaction of β-phenethylamine with ammonium thiocyanate gives the thiourea (2). Treatment of that product with phenacyl bromide produces fanetizole (3).[1]

Fanetizole synthesis

References

  1. ^ Lombardino, J. G.; 1981, U.S. patent 4,307,106
  • v
  • t
  • e
Histamine receptor modulators
H1
Agonists
Antagonists
  • Unknown/unsorted: Azanator
  • Belarizine
  • Elbanizine
  • Flotrenizine
  • GSK1004723
  • Napactadine
  • Tagorizine
  • Trelnarizine
  • Trenizine
H2
Agonists
Antagonists
H3
Agonists
Antagonists
H4
Agonists
Antagonists
See also
Receptor/signaling modulators
Monoamine metabolism modulators
Monoamine reuptake inhibitors
  • v
  • t
  • e
Drugs for peptic ulcer and GERD/GORD (A02B)
H2 antagonists ("-tidine")
Prostaglandins (E)/
analogues ("-prost-")
Proton-pump inhibitors
("-prazole")
Potassium-competitive
acid blockers ("-prazan")
Others
Combinations
  • See also: Helicobacter pylori eradication protocols