Fluoroacetyl chloride
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Names | |||
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Preferred IUPAC name Fluoroacetyl chloride | |||
Other names 2-Fluoroacetyl chloride Fluoroethanoyl chloride | |||
Identifiers | |||
CAS Number |
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3D model (JSmol) |
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ChemSpider |
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ECHA InfoCard | 100.006.022 | ||
PubChem CID |
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UNII |
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CompTox Dashboard (EPA) |
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InChI
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Properties | |||
Chemical formula | C2H2ClFO | ||
Molar mass | 96.49 g·mol−1 | ||
Boiling point | 70 to 71 °C (158 to 160 °F; 343 to 344 K) at 755 mmHg[1] | ||
Hazards | |||
NFPA 704 (fire diamond) | 4 1 2 | ||
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references |
Chemical compound
Fluoroacetyl chloride is an acyl chloride.
In 1948, William E. Truce of Purdue University described a synthesis of fluoroacetyl chloride which was undertaken "because of its potential value for introducing the group, —COCH2F, into organic molecules."[1] In this synthesis, he reacted sodium fluoroacetate with phosphorus pentachloride to obtain the desired compound.
See also
- Fluoroacetic acid
- Methyl fluoroacetate
References
- ^ a b Truce, William E. (August 1948). "The Preparation of Fluoroacetyl Chloride". Journal of the American Chemical Society. 70 (88): 2828. doi:10.1021/ja01188a524.
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Derivatives of fluoroacetic acid and 2-fluoroethanol
- Aluminum fluoroacetate
- Ammonium fluoroacetate
- Barium fluoroacetate
- Cadmium fluoroacetate
- Calcium fluoroacetate
- Cupric fluoroacetate
- Potassium fluoroacetate
- Sodium fluoroacetate
- Thallous fluoroacetate
- Triethyllead fluoroacetate
- Allyl fluoroacetate
- Butyl fluoroacetate
- Cetyl fluoroacetate
- Cholesteryl fluoroacetate
- Ethyl fluoroacetate
- 2-Ethylhexyl fluoroacetate
- Fluoroacetylcholine
- Fluoroaspirin
- Fluoroethyl fluoroacetate
- Isopropyl fluoroacetate
- Methyl fluoroacetate
- Methylene bis(fluoroacetate)
- Phenyl fluoroacetate
- Propyl fluoroacetate
- Bis(2-fluoroethyl) carbonate
- Bis(2-fluoroethyl) hydrogen phosphite
- Bis(2-fluoroethyl) phosphorofluoridate
- Bis(2-fluoroethyl) sulfate
- Bis(2-fluoroethyl) sulfite
- Fluenetil
- Fluoroethyl acetate
- Fluoroethyl chloroacetate
- Fluoroethyl chloroformate
- Fluoroethyl chlorosulfonate
- Fluoroethyl fluoroacetate
- Fluoroethyl nitrite
- Fluoroethyl trichloroacetate
- Tetrakis(2-fluoroethyl) orthosilicate
- TL-790
- TL-821
- Tris(2-fluoroethyl) arsenite
- Tris(2-fluoroethyl) borate
- Tris(2-fluoroethyl) phosphite
- Tris(2-fluoroethyl) orthoformate
- Fluoroacetamide
- Fluoroacetanilide
- Nissol
- Bis(2-fluoroethyl)ether
- 2-chloroethyl fluorothioacetate
- Fluoroacetic anhydride
- Fluoroacetyl chloride
- Fluoroacetyl fluoride
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