Gamithromycin
Medication
- US DailyMed: Gamithromycin
administration
- QJ01FA95 (WHO)
- US: ℞-only[1][2]
- EU: Rx-only[3][4]
- (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-11-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-2-ethyl-3,4,10-trihydroxy-13-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,8,10,12,14-hexamethyl-7-propyl-1-oxa-7-azacyclopentadecan-15-one
- 145435-72-9
- 59364992
- DB11416
- 28530824
- ZE856183S0
- D06598
- CHEBI:195437
- ChEMBL2107342
- DTXSID90904260
- Interactive image
- [H][C@@]1(C[C@@](C)(OC)[C@@H](O)[C@H](C)O1)O[C@H]1[C@H](C)[C@@H](O[C@]2([H])O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)N(CCC)C[C@H](C)[C@@H](O)[C@](C)(O)[C@@H](CC)OC(=O)[C@@H]1C
- InChI=1S/C40H76N2O12/c1-15-17-42-21-22(3)33(44)40(11,48)29(16-2)52-36(46)26(7)32(53-30-20-39(10,49-14)34(45)27(8)51-30)25(6)35(38(9,47)19-23(42)4)54-37-31(43)28(41(12)13)18-24(5)50-37/h22-35,37,43-45,47-48H,15-21H2,1-14H3/t22-,23+,24+,25-,26+,27-,28-,29+,30-,31+,32-,33+,34-,35+,37-,38+,39+,40+/m0/s1
- Key:VWAMTBXLZPEDQO-UZSBJOJWSA-N
Gamithromycin, sold under the brand name Zactran, is a veterinary medication used for the treatment of cattle, pigs, and sheep.[3][4][5] It is a macrolide antibacterial.[3][4] It is a 7a-azalide.[6]
It was approved for veterinary use in the European Union in 2008.[3][4]
Veterinary uses
In the EU, gamithromycin is indicated for the treatment and prevention of bovine respiratory disease in cattle, swine respiratory disease in pigs, and infectious pododermatitis (foot rot) in sheep.[3][4][6]
In the US, gamithromycin is indicated for the treatment of bovine respiratory disease in cattle.[1]
References
- ^ a b "Zactran - gamithromycin injection, solution". DailyMed. 17 April 2024. Retrieved 29 June 2024.
- ^ "Zactran". U.S. Food and Drug Administration (FDA). Retrieved 29 June 2024.
- ^ a b c d e "Zactran EPAR". European Medicines Agency. 1 August 2008. Retrieved 29 June 2024.
- ^ a b c d e "Zactran PI". Union Register of veterinary medicinal products. 28 July 2008. Retrieved 29 June 2024.
- ^ Budde JA, McCluskey DM (2023). "Gamithromycin". Plumb's Veterinary Drug Handbook (10th ed.). Tulsa, OK: Educational Concepts, LLC, dba VetMedux. p. 571. ISBN 978-1-394-17220-7.
- ^ a b "Gamithromycin". Inxight Drugs. Retrieved 29 June 2024.
This article incorporates text from this source, which is in the public domain.
External links
- "Gamithromycin (Code C170019)". NCI Thesaurus.
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