ITGA6 |
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Identifiers |
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Aliases | ITGA6, CD49f, ITGA6B, VLA-6, integrin subunit alpha 6, JEB6 |
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External IDs | OMIM: 147556; MGI: 96605; HomoloGene: 20091; GeneCards: ITGA6; OMA:ITGA6 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 2 (human)[1] |
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| Band | 2q31.1 | Start | 172,427,354 bp[1] |
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End | 172,506,459 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 2 (mouse)[2] |
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| Band | 2 C2- C3|2 42.79 cM | Start | 71,575,960 bp[2] |
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End | 71,688,760 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - tibial nerve
- sural nerve
- spinal ganglia
- trigeminal ganglion
- epithelium of colon
- Achilles tendon
- rectum
- pylorus
- tendon of biceps brachii
- duodenum
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| Top expressed in | - sciatic nerve
- epithelium of stomach
- secondary oocyte
- atrium
- epithelium of lens
- left lung lobe
- crypt of lieberkuhn of small intestine
- endothelial cell of lymphatic vessel
- pyloric antrum
- left colon
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| More reference expression data |
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BioGPS |
| More reference expression data |
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Gene ontology |
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Molecular function | - metal ion binding
- integrin binding
- protein binding
- laminin binding
- neuregulin binding
- protein-containing complex binding
- insulin-like growth factor I binding
- cadherin binding
| Cellular component | - integral component of membrane
- membrane
- focal adhesion
- basal part of cell
- plasma membrane
- hemidesmosome
- basement membrane
- cell surface
- integrin complex
- basal plasma membrane
- basolateral plasma membrane
- external side of plasma membrane
- integrin alpha6-beta4 complex
- filopodium
| Biological process | - cellular response to extracellular stimulus
- hemidesmosome assembly
- renal system development
- nail development
- positive regulation of cell-cell adhesion
- filopodium assembly
- negative regulation of extrinsic apoptotic signaling pathway
- extracellular matrix organization
- odontogenesis of dentin-containing tooth
- cell-substrate adhesion
- positive regulation of GTPase activity
- cell adhesion
- cell adhesion mediated by integrin
- brown fat cell differentiation
- positive regulation of apoptotic process
- cell-substrate junction assembly
- integrin-mediated signaling pathway
- positive regulation of phosphorylation
- cell-matrix adhesion
- digestive tract development
- ectodermal cell differentiation
- leukocyte migration
- skin development
- positive regulation of transcription by RNA polymerase II
- amelogenesis
- cellular response to organic cyclic compound
- positive regulation of cell-substrate adhesion
- positive regulation of cell migration
- cell-cell adhesion
- positive regulation of neuron projection development
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | NM_000210 NM_001079818 NM_001316306 NM_001365529 NM_001365530
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NM_001394928 |
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RefSeq (protein) | |
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NP_000201 NP_001073286 NP_001303235 NP_001352458 NP_001352459 |
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NP_001264899 NP_032423 NP_001393187 |
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Location (UCSC) | Chr 2: 172.43 – 172.51 Mb | Chr 2: 71.58 – 71.69 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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