Isojacareubin
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IUPAC name 6,10,11-Trihydroxy-3,3-dimethylpyrano[2,3-c]xanthen-7-one | |
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Properties | |
Chemical formula | C18H14O6 |
Molar mass | 326.304 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references |
Chemical compound
Isojacareubin is a xanthonoid natural product found in Hypericum japonicum.[1]
It has been shown to have antibacterial activity. Isojacareubin also inhibits protein kinase C isoforms, and has activity in an animal model of hepatocellular carcinoma.[2]
References
- ^ Zuo, GY; An, J; Han, J; Zhang, YL; Wang, GC; Hao, XY; Bian, ZQ (2012). "Isojacareubin from the Chinese Herb Hypericum japonicum: Potent Antibacterial and Synergistic Effects on Clinical Methicillin-Resistant Staphylococcus aureus (MRSA)". International Journal of Molecular Sciences. 13 (7): 8210–8. doi:10.3390/ijms13078210. PMC 3430230. PMID 22942699.
- ^ Xing Yuan, Hao Chen, Xia Li, Ming Dai, Huawu Zeng, Lei Shan, Qingyan Sun & Weidong Zhang (2015). "Inhibition of protein kinase C by isojacareubin suppresses hepatocellular carcinoma metastasis and induces apoptosis in vitro and in vivo". Scientific Reports. 5: 12889. Bibcode:2015NatSR...512889Y. doi:10.1038/srep12889. PMC 4526861. PMID 26245668.
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Types of xanthonoids
- Apetalinone A, B, C and D
- Bellidifolin
- Calozeyloxanthone
- Desoxygambogenin
- Desoxymorellin
- Euxanthone
- Forbesione
- Gambogellic acid
- Gambogenic acid
- Gambogenin
- Gambogenin dimethyl acetal
- Gambogic acid
- Gambogin
- Gaudichaudiic acid A, B, C, D and E
- Gaudichaudione A, B, C, D, E, F, G and H
- Hanburin
- Isogambogenin
- Isojacareubin
- Isomorellin
- Isomoreollin B
- Methylswertianin
- Morellic acid
- Morellin dimethyl acetal
- Moreollic acid
- Norathyriol
- Psorospermin
- 2,3′,4,6-tetrahydroxybenzophenone
- Tomentonone
- Zeyloxanthonone
- Euxanthic acid
- Isomangiferin
- Mangiferin
- Mangostin-3,6-di-O-glucoside
- Wubangziside A
- Wubangziside B
- Indian yellow
- Gartanin
- 8-disoxygartanin
- Normangostin
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