LMBRD1 |
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Identifiers |
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Aliases | LMBRD1, C6orf209, LMBD1, MAHCF, NESI, LMBR1 domain containing 1 |
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External IDs | OMIM: 612625; MGI: 1915671; HomoloGene: 10156; GeneCards: LMBRD1; OMA:LMBRD1 - orthologs |
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Gene location (Human) |
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![Chromosome 6 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/0/03/Ideogram_human_chromosome_6.svg/300px-Ideogram_human_chromosome_6.svg.png) | Chr. | Chromosome 6 (human)[1] |
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| Band | 6q13 | Start | 69,672,757 bp[1] |
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End | 69,867,236 bp[1] |
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Gene location (Mouse) |
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![Chromosome 1 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Ideogram_house_mouse_chromosome_1.svg/260px-Ideogram_house_mouse_chromosome_1.svg.png) | Chr. | Chromosome 1 (mouse)[2] |
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| Band | 1|1 A5 | Start | 24,717,711 bp[2] |
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End | 24,805,382 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - secondary oocyte
- retinal pigment epithelium
- islet of Langerhans
- olfactory bulb
- bronchial epithelial cell
- corpus callosum
- C1 segment
- Epithelium of choroid plexus
- skin of thigh
- cerebellar vermis
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| Top expressed in | - saccule
- ectoderm
- otic vesicle
- otic placode
- spermatid
- Epithelium of choroid plexus
- neural layer of retina
- superior frontal gyrus
- stroma of bone marrow
- anterior horn of spinal cord
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/d/d4/PBB_GE_LMBRD1_218191_s_at_fs.png/250px-PBB_GE_LMBRD1_218191_s_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - cobalamin binding
- insulin receptor binding
- ABC-type vitamin B12 transporter activity
| Cellular component | - integral component of membrane
- clathrin-coated endocytic vesicle
- lysosomal membrane
- plasma membrane
- lysosome
- membrane
| Biological process | - cobalamin metabolic process
- insulin receptor internalization
- negative regulation of glucose import
- negative regulation of insulin receptor signaling pathway
- negative regulation of protein kinase B signaling
- viral process
- cobalamin transport
- transport
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_018368 NM_001363722 NM_001367271 NM_001367272 |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 6: 69.67 – 69.87 Mb | Chr 1: 24.72 – 24.81 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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