LRRN1

Protein-coding gene in the species Homo sapiens
LRRN1
Identifiers
AliasesLRRN1, FIGLER3, NLRR-1, leucine rich repeat neuronal 1, NLRR1
External IDsMGI: 106038; HomoloGene: 32036; GeneCards: LRRN1; OMA:LRRN1 - orthologs
Gene location (Human)
Chromosome 3 (human)
Chr.Chromosome 3 (human)[1]
Chromosome 3 (human)
Genomic location for LRRN1
Genomic location for LRRN1
Band3p26.2Start3,799,431 bp[1]
End3,849,834 bp[1]
Gene location (Mouse)
Chromosome 6 (mouse)
Chr.Chromosome 6 (mouse)[2]
Chromosome 6 (mouse)
Genomic location for LRRN1
Genomic location for LRRN1
Band6|6 E1Start107,506,729 bp[2]
End107,547,175 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • ventricular zone

  • ganglionic eminence

  • spinal ganglia

  • retinal pigment epithelium

  • superior vestibular nucleus

  • caudate nucleus

  • pons

  • putamen

  • nucleus accumbens

  • trigeminal ganglion
Top expressed in
  • pontine nuclei

  • olfactory epithelium

  • deep cerebellar nuclei

  • vestibular sensory epithelium

  • lower lip

  • lobe of cerebellum

  • cerebellar vermis

  • medial vestibular nucleus

  • mammillary body

  • ventral tegmental area
More reference expression data
BioGPS
n/a
Orthologs
SpeciesHumanMouse
Entrez

57633

16979

Ensembl

ENSG00000175928

ENSMUSG00000034648

UniProt

Q6UXK5

Q61809

RefSeq (mRNA)

NM_020873
NM_001324188
NM_001324189

NM_008516

RefSeq (protein)

NP_001311117
NP_001311118
NP_065924

NP_032542

Location (UCSC)Chr 3: 3.8 – 3.85 MbChr 6: 107.51 – 107.55 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Leucine-rich repeat neuronal protein 1 is a protein that in humans is encoded by the LRRN1 gene.[5][6]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000175928 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034648 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Nagase T, Kikuno R, Ishikawa K, Hirosawa M, Ohara O (Sep 2000). "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (2): 143–50. doi:10.1093/dnares/7.2.143. PMID 10819331.
  6. ^ "Entrez Gene: LRRN1 leucine rich repeat neuronal 1".

Further reading

  • Ohira M, Morohashi A, Nakamura Y, et al. (2003). "Neuroblastoma oligo-capping cDNA project: toward the understanding of the genesis and biology of neuroblastoma". Cancer Lett. 197 (1–2): 63–8. doi:10.1016/S0304-3835(03)00085-5. PMID 12880961.
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMC 2286551. PMID 15340161.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.


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