MICALL1

Protein-coding gene in the species Homo sapiens

MICALL1
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

2KSP

Identifiers
AliasesMICALL1, MICAL-L1, MIRAB13, MICAL like 1
External IDsMGI: 105870; HomoloGene: 24911; GeneCards: MICALL1; OMA:MICALL1 - orthologs
Gene location (Human)
Chromosome 22 (human)
Chr.Chromosome 22 (human)[1]
Chromosome 22 (human)
Genomic location for MICALL1
Genomic location for MICALL1
Band22q13.1Start37,905,657 bp[1]
End37,942,822 bp[1]
Gene location (Mouse)
Chromosome 15 (mouse)
Chr.Chromosome 15 (mouse)[2]
Chromosome 15 (mouse)
Genomic location for MICALL1
Genomic location for MICALL1
Band15 E1|15 37.7 cMStart79,108,898 bp[2]
End79,136,900 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • gingival epithelium

  • sperm

  • body of stomach

  • mucosa of esophagus

  • hair follicle

  • placenta

  • sural nerve

  • human penis

  • muscle layer of sigmoid colon

  • skin of leg
Top expressed in
  • ascending aorta

  • aortic valve

  • molar

  • gastrula

  • vestibular membrane of cochlear duct

  • atrium

  • otolith organ

  • utricle

  • suprachiasmatic nucleus

  • lip
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
  • metal ion binding
  • phosphatidic acid binding
  • protein binding
  • identical protein binding
  • cadherin binding
Cellular component
  • endosome
  • late endosome
  • membrane
  • late endosome membrane
  • recycling endosome membrane
  • trans-Golgi network
  • early endosome
  • endosome membrane
  • extrinsic component of membrane
  • intracellular anatomical structure
Biological process
  • cellular response to nerve growth factor stimulus
  • endocytosis
  • protein targeting to membrane
  • receptor-mediated endocytosis
  • plasma membrane tubulation
  • endocytic recycling
  • protein transport
  • protein localization to endosome
  • neuron projection development
  • slow endocytic recycling
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

85377

27008

Ensembl

ENSG00000100139

ENSMUSG00000033039

UniProt

Q8N3F8

Q8BGT6

RefSeq (mRNA)

NM_033386

NM_177461

RefSeq (protein)

NP_203744

NP_803412

Location (UCSC)Chr 22: 37.91 – 37.94 MbChr 15: 79.11 – 79.14 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

MICAL-like 1, also known as MICALL1, is a human gene.[5]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000100139 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000033039 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: MICALL1 MICAL-like 1".

Further reading

  • Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. Bibcode:1999Natur.402..489D. doi:10.1038/990031. PMID 10591208.
  • Hirosawa M, Nagase T, Murahashi Y, et al. (2001). "Identification of novel transcribed sequences on human chromosome 22 by expressed sequence tag mapping". DNA Res. 8 (1): 1–9. doi:10.1093/dnares/8.1.1. PMID 11258795.
  • Marzesco AM, Dunia I, Pandjaitan R, et al. (2002). "The small GTPase Rab13 regulates assembly of functional tight junctions in epithelial cells". Mol. Biol. Cell. 13 (6): 1819–31. doi:10.1091/mbc.02-02-0029. PMC 117606. PMID 12058051.
  • Terman JR, Mao T, Pasterkamp RJ, et al. (2002). "MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion". Cell. 109 (7): 887–900. doi:10.1016/S0092-8674(02)00794-8. PMID 12110185.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Weide T, Teuber J, Bayer M, Barnekow A (2003). "MICAL-1 isoforms, novel rab1 interacting proteins". Biochem. Biophys. Res. Commun. 306 (1): 79–86. doi:10.1016/S0006-291X(03)00918-5. PMID 12788069.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
  • Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. 14 (16): 1436–50. Bibcode:2004CBio...14.1436J. doi:10.1016/j.cub.2004.07.051. PMID 15324660.
  • Collins JE, Wright CL, Edwards CA, et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMC 545604. PMID 15461802.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.


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