MON2

Protein-coding gene in the species Homo sapiens
MON2
Identifiers
AliasesMON2, MON2 homolog, regulator of endosome-to-Golgi trafficking
External IDsOMIM: 616822; MGI: 1914324; HomoloGene: 44309; GeneCards: MON2; OMA:MON2 - orthologs
Gene location (Human)
Chromosome 12 (human)
Chr.Chromosome 12 (human)[1]
Chromosome 12 (human)
Genomic location for MON2
Genomic location for MON2
Band12q14.1Start62,466,817 bp[1]
End62,600,476 bp[1]
Gene location (Mouse)
Chromosome 10 (mouse)
Chr.Chromosome 10 (mouse)[2]
Chromosome 10 (mouse)
Genomic location for MON2
Genomic location for MON2
Band10|10 D2Start122,827,965 bp[2]
End122,912,410 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • body of pancreas

  • tibia

  • Achilles tendon

  • mucosa of paranasal sinus

  • tibial nerve

  • corpus callosum

  • right uterine tube

  • skin of leg

  • left ovary

  • skin of abdomen
Top expressed in
  • stroma of bone marrow

  • calvaria

  • lacrimal gland

  • hand

  • granulocyte

  • parotid gland

  • lip

  • foot

  • deep cerebellar nuclei

  • otolith organ
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • protein binding
Cellular component
  • extracellular exosome
  • cytosol
Biological process
  • protein transport
  • Golgi to endosome transport
  • transport
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

23041

67074

Ensembl

ENSG00000061987

ENSMUSG00000034602

UniProt

Q7Z3U7

Q80TL7

RefSeq (mRNA)

NM_001278469
NM_001278470
NM_001278471
NM_001278472
NM_015026

NM_001163024
NM_001163025
NM_153395

RefSeq (protein)
NP_001265398
NP_001265399
NP_001265400
NP_001265401
NP_055841

NP_001265400.1

NP_001156496
NP_001156497
NP_700444

Location (UCSC)Chr 12: 62.47 – 62.6 MbChr 10: 122.83 – 122.91 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Protein MON2 homolog is a protein that in humans is encoded by the MON2 gene.[5][6]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000061987 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034602 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Gillingham AK, Whyte JR, Panic B, Munro S (Jan 2006). "Mon2, a relative of large Arf exchange factors, recruits Dop1 to the Golgi apparatus". J Biol Chem. 281 (4): 2273–80. doi:10.1074/jbc.M510176200. PMID 16301316.
  6. ^ "Entrez Gene: MON2 MON2 homolog (S. cerevisiae)".

Further reading

  • Kikuno R, Nagase T, Ishikawa K, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (3): 197–205. doi:10.1093/dnares/6.3.197. PMID 10470851.
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216. S2CID 11683986.
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.


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