N-t-BOC-MDMA
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Formula | C16H23NO4 |
Molar mass | 293.363 g·mol−1 |
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N-t-BOC-MDMA is a chemical compound which can be both a synthetic precursor to, or a prodrug of the empathogenic drug MDMA. It was first identified in Australia in 2015 as a seizure by customs, and has subsequently been found in China, the Netherlands and other European countries. Originally it was thought to be intended as a non-illegal form of MDMA which could be easily converted into the prohibited final product after importation, however one seizure by police found N-t-BOC-MDMA in the process of being pressed into pills, and experiments with simulated gastric fluid confirmed that it can be broken down to MDMA by human stomach acid. Similar N-protected compounds such as N-t-BOC-methamphetamine, N-p-tosyl-methamphetamine, N-t-BOC-ketamine, N-t-BOC-norketamine, and N-methoxycarbonyl-MDA have also been encountered by law enforcement.[1][2][3][4][5][6][7]
Legal status
N-t-BOC-MDMA has been specifically listed as an illicit drug in Singapore and South Korea,[8][9] but is also likely to be controlled by general drug analogue laws in various other countries.
See also
- 1-Boc-4-AP - a masked fentanyl precursor
- Gabapentin enacarbil
- O-Acetylpsilocin
- Lys-MDA
References
- ^ Collins M, Donnelly C, Cameron S, Tahtouh M, Salouros H (March 2017). "Identification and characterization of N-tert-butoxycarbonyl-MDMA: a new MDMA precursor". Drug Testing and Analysis. 9 (3): 399–404. doi:10.1002/dta.2059. PMID 27574107.
- ^ Sugie KI, Kurakami D, Akutsu M, Saito K (2018). "Rapid detection of tert-butoxycarbonyl-methamphetamine by direct analysis in real time time-of-flight mass spectrometry". Forensic Toxicology. 36 (2): 261–269. doi:10.1007/s11419-017-0400-y. PMC 6002434. PMID 29963202.
- ^ Salouros H (2018). "Illicit drug chemical profiling: current and future state". Australian Journal of Forensic Sciences. 50 (6): 689–696. doi:10.1080/00450618.2018.1424244. S2CID 80559699.
- ^ Collins M, Bhattarai A, Salouros H (2018). "Another chemically masked drug: p-tosyl methylamphetamine". Drug Testing and Analysis. 10 (5): 898–905. doi:10.1002/dta.2363. PMID 29388381.
- ^ Johnson CS, Bogun B (2019). "Chemical camouflage: illicit drug concealment using di-tert-butyldicarbonate". Australian Journal of Forensic Sciences. 51: S217–S219. doi:10.1080/00450618.2019.1569135. S2CID 86747489.
- ^ European Monitoring Centre for Drugs and Drug Addiction (2019). "Drug precursor developments in the European Union" (PDF). EMCDDA Papers. Luxembourg: Publications Office of the European Union.
- ^ "Prosecutors Detail 500 Kilogram Ketamine Precursor Raid". ICRT.com. 3 March 2020.
- ^ "Singapore Misuse of Drugs (Amendment No. 2) Regulations 2020".
- ^ "Han-soo L. Ministry lists 10 substances on temporary narcotics list". Korea Biomedical Review. 11 May 2018.
- v
- t
- e
amines
(other than
cathinones)
- Unfused benzene ring: 3-CMA
- 4-CAB
- 4-FA
- 4-MA
- 4-MMA
- 4-FMA
- 4-MTA
- 4,4'-DMAR
- Ariadne
- Metaescaline
- MMA
- PMA
- PMEA
- PMMA
- mMMA
Benzodioxine: EDMA
Benzodioxoles: Phenethylamine: { Lophophine } - Amphetamines: { 2-Methyl-MDA
- 2,3-MDA
- 3,4-MDA (tenamfetamine)
- 5-Methyl-MDA
- 6-Methyl-MDA
- DFMDA
- DMMDA
- DMMDA-2
- EIDA
- Lys-MDA
- MDEA
- MDMA (midomafetamine)
- MDMOH
- MDOH
- MMDA
- MMDA-2
- MMDMA
- N-t-BOC-MDMA }
- 1-Phenylbutan-2-amines: { BDB
- EBDB
- MBDB }
- Phentermines: { MDMP
- MDPH }
Benzofurans, dihydrobenzofurans and benzothiophenes: 2-MAPB - 5-APB
- 5-APDB
- 5-EAPB
- 5-MAPB
- 5-MAPDB
- 5-MAPBT
- 5-MBPB
- 6-APB
- 6-APDB
- 6-EAPB
- 6-MAPB
- 6-MAPDB
- IBF5MAP
Indanes: 5-APDI - 5-MAPDI
Indoles: 5-IT - 6-API
Naphthalenes: Methamnetamine - Naphthylaminopropane
Tetralin: 6-APT
alkylamines