Ormetoprim
Chemical compound
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Clinical data | |
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Other names | Ormethoprim |
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ECHA InfoCard | 100.027.497 ![]() |
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Formula | C14H18N4O2 |
Molar mass | 274.324 g·mol−1 |
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Ormetoprim is an antibiotic used in veterinary medicine. Typically it is used in combination with sulfadimethoxine, and it is used in the poultry[1] and aquaculture industries.[2]
Ormetoprim, like other diaminopyrimidines such as trimethoprim, inhibits the reduction of dihydrofolic acid to tetrahydrofolic acid by bacterial cells.[3]
References
- ^ Hofacre CL, Fricke JA, Inglis T (2013). "Antimicrobial Drug Use in Poultry". Antimicrobial Therapy in Veterinary Medicine. pp. 569–587. doi:10.1002/9781118675014.ch34. ISBN 978-0-470-96302-9.
- ^ Singh M, Singh P (2018). "Drugs and chemicals applied in aquaculture industry: A review of commercial availability, recommended dosage and mode of application" (PDF). Journal of Entomology and Zoology Studies. 6 (6): 903–907.
- ^ "PRIMOR - sulfadimethoxine and ormetoprim tablet". DailyMed. U.S. National Library of Medicine.
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(inhibit bacterial
purine metabolism,
thereby inhibiting
DNA and RNA
synthesis)
DHFR inhibitor |
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Sulfonamides (DHPS inhibitor) |
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Combinations |
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Other DHPS inhibitors |
(inhibit bacterial
topoisomerase
and/or DNA gyrase,
thereby inhibiting
DNA replication)
1st generation | |||||||||
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Fluoroquinolones |
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Newer non-fluorinated | |||||||||
Related (DG) |
inhibitors
Nitroimidazole derivatives |
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Rifamycins/ RNA polymerase | |
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Lipiarmycins |
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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