Oxiperomide
Chemical compound
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Routes of administration | Oral |
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Formula | C20H23N3O2 |
Molar mass | 337.423 g·mol−1 |
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Oxiperomide is an antipsychotic.[1] Clinical trials demonstrated that it can reduce dyskinesia in patients with Parkinson's disease who are taking dopamine agonists without increasing Parkinsonian symptoms. It does this by selectively antagonizing dopamine receptors.[2][3] Further development of this drug is not available. It appears to have never been marketed.
See also
- Benperidol
- Neflumozide
References
- ^ Elks J (1990). "Oxiperomide". The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Dordrecht: Springer. ISBN 978-1-4757-2085-3.
- ^ Bédard P, Parkes JD, Marsden CD (April 1978). "Effect of new dopamine-blocking agent (oxiperomide) on drug-induced dyskinesias in Parkinson's disease and spontaneous dyskinesias". British Medical Journal. 1 (6118): 954–956. doi:10.1136/bmj.1.6118.954. PMC 1603806. PMID 638546.
- ^ Casey DE, Gerlach J (March 1980). "Oxiperomide in tardive dyskinesia". Journal of Neurology, Neurosurgery, and Psychiatry. 43 (3): 264–267. doi:10.1136/jnnp.43.3.264. PMC 490519. PMID 7373324.