PHYHIP

Protein-coding gene in the species Homo sapiens
PHYHIP
Identifiers
AliasesPHYHIP, DYRK1AP3, PAHX-AP, PAHXAP1, phytanoyl-CoA 2-hydroxylase interacting protein
External IDsOMIM: 608511; MGI: 1860417; HomoloGene: 8847; GeneCards: PHYHIP; OMA:PHYHIP - orthologs
Gene location (Human)
Chromosome 8 (human)
Chr.Chromosome 8 (human)[1]
Chromosome 8 (human)
Genomic location for PHYHIP
Genomic location for PHYHIP
Band8p21.3Start22,219,703 bp[1]
End22,232,101 bp[1]
Gene location (Mouse)
Chromosome 14 (mouse)
Chr.Chromosome 14 (mouse)[2]
Chromosome 14 (mouse)
Genomic location for PHYHIP
Genomic location for PHYHIP
Band14|14 D2Start70,694,916 bp[2]
End70,706,272 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right hemisphere of cerebellum

  • middle frontal gyrus

  • Brodmann area 10

  • paraflocculus of cerebellum

  • right frontal lobe

  • Brodmann area 9

  • nucleus accumbens

  • putamen

  • caudate nucleus

  • frontal pole
Top expressed in
  • dentate gyrus of hippocampal formation granule cell

  • superior frontal gyrus

  • cerebellar cortex

  • primary visual cortex

  • cerebellar vermis

  • lobe of cerebellum

  • olfactory tubercle

  • piriform cortex

  • prefrontal cortex

  • subiculum
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • protein tyrosine kinase binding
Cellular component
  • cytoplasm
Biological process
  • xenophagy
  • positive regulation of defense response to virus by host
  • protein localization
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

9796

105653

Ensembl

ENSG00000168490

ENSMUSG00000003469

UniProt

Q92561

Q8K0S0

RefSeq (mRNA)

NM_001099335
NM_014759
NM_001363311
NM_001363312

NM_145981

RefSeq (protein)

NP_001092805
NP_055574
NP_001350240
NP_001350241

NP_666093

Location (UCSC)Chr 8: 22.22 – 22.23 MbChr 14: 70.69 – 70.71 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Phytanoyl-CoA 2-hydroxylase interacting protein is a protein that in humans is encoded by the PHYHIP gene. [5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000168490 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000003469 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Phytanoyl-CoA 2-hydroxylase interacting protein". Retrieved 2016-07-15.

Further reading

  • Bescond M, Rahmani Z (2005). "Dual-specificity tyrosine-phosphorylated and regulated kinase 1A (DYRK1A) interacts with the phytanoyl-CoA alpha-hydroxylase associated protein 1 (PAHX-AP1), a brain specific protein". Int. J. Biochem. Cell Biol. 37 (4): 775–83. doi:10.1016/j.biocel.2004.12.006. PMID 15694837.


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