Pyrogallol hydroxytransferase

In enzymology, a pyrogallol hydroxytransferase (EC 1.97.1.2) is an enzyme that catalyzes the chemical reaction

1,2,3,5-tetrahydroxybenzene + 1,2,3-trihydroxybenzene ${\displaystyle \rightleftharpoons }$ 1,3,5-trihydroxybenzene + 1,2,3,5-tetrahydroxybenzene

Thus, the two substrates of this enzyme are 1,2,3,5-tetrahydroxybenzene and 1,2,3-trihydroxybenzene (pyrogallol), whereas its two products are 1,3,5-trihydroxybenzene (phloroglucinol) and 1,2,3,5-tetrahydroxybenzene.

This enzyme participates in benzoic acid degradation via CoA ligation.

This enzyme belongs to the family of oxidoreductases. The systematic name of this enzyme class is 1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxytransferase. Other names in common use include 1,2,3,5-tetrahydroxybenzene hydroxyltransferase, 1,2,3,5-tetrahydroxybenzene:pyrogallol transhydroxylase, 1,2,3,5-tetrahydroxybenzene-pyrogallol hydroxyltransferase (transhydroxylase), pyrogallol hydroxyltransferase, 1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxyltransferase.

• Brune A, Schink B (February 1990). "Pyrogallol-to-phloroglucinol conversion and other hydroxyl-transfer reactions catalyzed by cell extracts of Pelobacter acidigallici". Journal of Bacteriology. 172 (2): 1070–6. doi:10.1128/jb.172.2.1070-1076.1990. PMC 208538. PMID 2298693.