RECQL5 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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4BK0, 5LB8, 5LB5, 5LBA, 5LB3 |
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Identifiers |
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Aliases | RECQL5, RECQ5, RecQ like helicase 5 |
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External IDs | OMIM: 603781; MGI: 2156841; HomoloGene: 31232; GeneCards: RECQL5; OMA:RECQL5 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 17 (human)[1] |
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| Band | 17q25.1 | Start | 75,626,845 bp[1] |
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End | 75,667,189 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 11 (mouse)[2] |
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| Band | 11|11 E2 | Start | 115,783,421 bp[2] |
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End | 115,824,303 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - right lobe of thyroid gland
- right uterine tube
- left lobe of thyroid gland
- left testis
- anterior pituitary
- right testis
- sural nerve
- skin of abdomen
- body of stomach
- skin of leg
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| Top expressed in | - granulocyte
- zygote
- spermatid
- neural layer of retina
- secondary oocyte
- lip
- tail of embryo
- corneal stroma
- ventricular zone
- plantaris muscle
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| More reference expression data |
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BioGPS |
| More reference expression data |
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Gene ontology |
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Molecular function | - RNA polymerase II complex binding
- nucleotide binding
- helicase activity
- DNA helicase activity
- nucleic acid binding
- hydrolase activity
- ATP binding
- DNA binding
- 3'-5' DNA helicase activity
- four-way junction helicase activity
- protein binding
- identical protein binding
| Cellular component | - RNA polymerase II, holoenzyme
- nucleoplasm
- nucleus
- chromosome
- cytoplasm
- cytosol
| Biological process | - DNA recombination
- DNA metabolic process
- negative regulation of transcription elongation from RNA polymerase II promoter
- cellular response to DNA damage stimulus
- cell division
- chromosome separation
- DNA replication
- cell cycle
- DNA repair
- DNA duplex unwinding
- double-strand break repair via homologous recombination
- cellular response to camptothecin
- replication-born double-strand break repair via sister chromatid exchange
- negative regulation of double-strand break repair via homologous recombination
- mitotic cell cycle
- mitotic sister chromatid segregation
- response to X-ray
- negative regulation of mitotic cell cycle
- DNA unwinding involved in DNA replication
- metabolism
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001003715 NM_001003716 NM_004259 |
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RefSeq (protein) | |
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NP_001003715 NP_001003716 NP_004250 |
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Location (UCSC) | Chr 17: 75.63 – 75.67 Mb | Chr 11: 115.78 – 115.82 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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