RNF220

Protein-coding gene in the species Homo sapiens
RNF220
Identifiers
AliasesRNF220, C1orf164, ring finger protein 220, HLD23
External IDsOMIM: 616136; MGI: 1913993; HomoloGene: 10036; GeneCards: RNF220; OMA:RNF220 - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for RNF220
Genomic location for RNF220
Band1p34.1Start44,405,194 bp[1]
End44,651,724 bp[1]
Gene location (Mouse)
Chromosome 4 (mouse)
Chr.Chromosome 4 (mouse)[2]
Chromosome 4 (mouse)
Genomic location for RNF220
Genomic location for RNF220
Band4|4 D1Start117,128,660 bp[2]
End117,354,249 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • C1 segment

  • prefrontal cortex

  • right frontal lobe

  • anterior cingulate cortex

  • corpus callosum

  • right hemisphere of cerebellum

  • Brodmann area 9

  • granulocyte

  • nucleus accumbens

  • amygdala
Top expressed in
  • tail of embryo

  • zygote

  • genital tubercle

  • spermatid

  • CA3 field

  • superior frontal gyrus

  • dentate gyrus of hippocampal formation granule cell

  • perirhinal cortex

  • neural layer of retina

  • entorhinal cortex
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • protein binding
  • metal ion binding
  • ubiquitin protein ligase activity
  • ubiquitin-protein transferase activity
  • transferase activity
Cellular component
  • cytoplasm
Biological process
  • protein autoubiquitination
  • protein ubiquitination
  • positive regulation of canonical Wnt signaling pathway
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

55182

66743

Ensembl

ENSG00000187147

ENSMUSG00000028677

UniProt

Q5VTB9

Q6PDX6

RefSeq (mRNA)
NM_018150
NM_001319956
NM_001319957
NM_001376486
NM_001376487

NM_001376488
NM_001376489
NM_016501

NM_025739
NM_001310729
NM_001310730
NM_001310731

RefSeq (protein)
NP_001306885
NP_001306886
NP_060620
NP_001363415
NP_001363416

NP_001363417
NP_001363418

NP_001297658
NP_001297659
NP_001297660
NP_080015

Location (UCSC)Chr 1: 44.41 – 44.65 MbChr 4: 117.13 – 117.35 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

RING finger protein 220 is a protein that in humans is encoded by the RNF220 gene.[5][6]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000187147 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028677 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (Nov 2000). "Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
  6. ^ "Entrez Gene: C1orf164 chromosome 1 open reading frame 164".

Further reading

  • Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. S2CID 13709685.
  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.


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