SH3BP1 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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4J9D, 4J9F |
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Identifiers |
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Aliases | SH3BP1, ARHGAP43, SH3 domain binding protein 1 |
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External IDs | OMIM: 617368; MGI: 104603; HomoloGene: 7534; GeneCards: SH3BP1; OMA:SH3BP1 - orthologs |
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Gene location (Human) |
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![Chromosome 22 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/6/62/Ideogram_human_chromosome_22.svg/300px-Ideogram_human_chromosome_22.svg.png) | Chr. | Chromosome 22 (human)[1] |
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| Band | 22q13.1 | Start | 37,634,654 bp[1] |
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End | 37,656,117 bp[1] |
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Gene location (Mouse) |
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![Chromosome 15 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/1/13/Ideogram_house_mouse_chromosome_15.svg/260px-Ideogram_house_mouse_chromosome_15.svg.png) | Chr. | Chromosome 15 (mouse)[2] |
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| Band | 15|15 E1 | Start | 78,783,968 bp[2] |
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End | 78,796,251 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - granulocyte
- monocyte
- mucosa of transverse colon
- skin of abdomen
- spleen
- skin of leg
- rectum
- lymph node
- blood
- appendix
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| Top expressed in | - granulocyte
- lip
- yolk sac
- esophagus
- mesenteric lymph nodes
- thymus
- superior frontal gyrus
- genital tubercle
- tail of embryo
- primary visual cortex
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - SH3 domain binding
- protein binding
- GTPase activator activity
- semaphorin receptor binding
| Cellular component | - cytoplasm
- exocyst
- lamellipodium
- phagocytic cup
- nucleus
- cytosol
- adherens junction
- bicellular tight junction
- cell junction
- cell projection
- cell leading edge
- intracellular anatomical structure
| Biological process | - signal transduction
- phagocytosis, engulfment
- actin filament organization
- regulation of actin filament depolymerization
- regulation of actin cytoskeleton organization
- cell junction assembly
- regulation of blood vessel endothelial cell migration
- establishment of epithelial cell apical/basal polarity
- negative regulation of small GTPase mediated signal transduction
- semaphorin-plexin signaling pathway
- phagocytosis
- cell migration
- positive regulation of GTPase activity
- filopodium assembly
- ruffle assembly
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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NM_009164 NM_001316684 NM_001316685 NM_001316686 |
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RefSeq (protein) | | |
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NP_001303613 NP_001303614 NP_001303615 NP_033190 |
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Location (UCSC) | Chr 22: 37.63 – 37.66 Mb | Chr 15: 78.78 – 78.8 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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