STNFR
Soluble tumor necrosis factor receptors (sTNFR) are the cleaved-off extracellular domains of transmembrane TNF receptors. They are proposed to enter the bloodstream either via shedding by the enzyme TACE or through exocytosis of the full-length receptor in exosome-like vesicles. Elevated levels of sTNFR are seen in inflammatory processes such as infection, malignancy and autoimmune diseases.[1]
References
- ^ Waetzig, Georg H.; Rosenstiel, Philip; Arlt, Alexander; Till, Andreas; Bräutigam, Karen; Schäfer, Heiner; Rose-John, Stefan; Seegert, Dirk; Schreiber, Stefan (2005). "Soluble tumor necrosis factor (TNF) receptor-1 induces apoptosis via reverse TNF signaling and autocrine transforming growth factor-β1". The FASEB Journal. 19 (1): 91–93. doi:10.1096/fj.04-2073fje. PMID 15514103. S2CID 86190513. Retrieved 4 February 2015.
- v
- t
- e
Cytokine receptor modulators
- See here instead.
Erythropoietin |
|
---|---|
G-CSF (CSF3) |
|
GM-CSF (CSF2) |
|
M-CSF (CSF1) |
|
SCF (c-Kit) |
|
Thrombopoietin |
|
IFNAR (α/β, I) |
|
---|---|
IFNGR (γ, II) |
|
IFNLR (λ, III) |
|
- See here instead.
- See here instead.
- See here instead.
JAK (inhibitors) |
| ||||||||
---|---|---|---|---|---|---|---|---|---|
Others |
|