Thrombopoietic agent

Drugs helps in inducing growth and maturation of megakaryocytes

Thrombopoietic agents are drugs that induce the growth and maturation of megakaryocytes.^[1] Some of them are currently in clinical use: romiplostim,^[2] eltrombopag, oprelvekin (a recombinant interleukin 11) and thrombopoietin. Several others are under clinical investigation such as lusutrombopag and avatrombopag.

References

^ Michael Clinton Perry. The Chemotherapy Source Book. Lippincott Williams & Wilkins, 2008 pg. 51
^ Romiplostim

Antihemorrhagics (B02)

Antihemorrhagics
(coagulation)

Systemic

Vitamin K	Phytomenadione (K₁) Menadione (K₃)
Coagulation factors	intrinsic: VIII/(Damoctocog alfa pegol, Efanesoctocog alfa, Efmoroctocog alfa, Moroctocog alfa, Susoctocog alfa, Turoctocog alfa, Valoctocogene roxaparvovec) IX/(Fidanacogene elaparvovec, Nonacog alfa) extrinsic: VII/Eptacog alfa common: X II/Thrombin I/Fibrinogen XIII/Catridecacog combinations: Prothrombin complex concentrate (II, VII, IX, X, protein C and S)
Other systemic	Batroxobin Carbazochrome Concizumab Etamsylate Fostamatinib thrombopoietin receptor agonist Romiplostim Avatrombopag Eltrombopag Lusutrombopag Rafutrombopag