VRK2 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | VRK2, vaccinia related kinase 2, VRK serine/threonine kinase 2 |
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External IDs | OMIM: 602169; MGI: 1917172; HomoloGene: 55966; GeneCards: VRK2; OMA:VRK2 - orthologs |
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EC number | 2.7.11.1 |
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Gene location (Human) |
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| Chr. | Chromosome 2 (human)[1] |
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| Band | 2p16.1 | Start | 57,907,629 bp[1] |
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End | 58,159,920 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 11 (mouse)[2] |
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| Band | 11|11 A3.3 | Start | 26,421,322 bp[2] |
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End | 26,543,999 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - monocyte
- Achilles tendon
- gonad
- corpus callosum
- right ventricle
- testicle
- islet of Langerhans
- epithelium of colon
- epithelium of nasopharynx
- rectum
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| Top expressed in | - fetal liver hematopoietic progenitor cell
- mesenteric lymph nodes
- blood
- granulocyte
- spleen
- spermatocyte
- thymus
- morula
- yolk sac
- subcutaneous adipose tissue
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - transferase activity
- nucleotide binding
- protein kinase activity
- protein domain specific binding
- kinase activity
- protein serine/threonine kinase activity
- protein binding
- ATP binding
- protein kinase binding
| Cellular component | - cytoplasm
- integral component of membrane
- endoplasmic reticulum membrane
- mitochondrial membranes
- membrane
- endoplasmic reticulum
- mitochondrion
- nucleus
- protein-containing complex
| Biological process | - regulation of MAPK cascade
- regulation of interleukin-1-mediated signaling pathway
- phosphorylation
- protein phosphorylation
- peptidyl-serine phosphorylation
- protein autophosphorylation
- cellular response to oxidative stress
- viral process
- regulation of cell shape
- peptidyl-threonine phosphorylation
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | NM_001130480 NM_001130481 NM_001130482 NM_001130483 NM_001288836
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NM_001288837 NM_001288838 NM_001288839 NM_006296 |
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RefSeq (protein) | NP_001123952 NP_001123953 NP_001123954 NP_001123955 NP_001275765
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NP_001275766 NP_001275767 NP_001275768 NP_006287 |
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Location (UCSC) | Chr 2: 57.91 – 58.16 Mb | Chr 11: 26.42 – 26.54 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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