ZMYM3

Protein-coding gene in the species Homo sapiens

ZMYM3

Identifiers

Aliases

ZMYM3, DXS6673E, MYM, XFIM, ZNF198L2, ZNF261, zinc finger MYM-type containing 3

External IDs

OMIM: 300061; MGI: 1927231; HomoloGene: 3736; GeneCards: ZMYM3; OMA:ZMYM3 - orthologs

Gene location (Human)

Chr.	X chromosome (human)^[1]

Band	Xq13.1	Start	71,239,624 bp^[1]
Band	Xq13.1	End	71,255,146 bp^[1]

Gene location (Mouse)

Chr.	X chromosome (mouse)^[2]

Band	X D\|X 44.1 cM	Start	101,404,384 bp^[2]
Band	X D\|X 44.1 cM	End	101,420,849 bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

right adrenal gland

right adrenal cortex

endothelial cell

right ovary

left ovary

left adrenal gland

left adrenal cortex

right uterine tube

embryo

secondary oocyte

Top expressed in

neural layer of retina

superior frontal gyrus

primary visual cortex

genital tubercle

dentate gyrus of hippocampal formation granule cell

cerebellar cortex

dorsomedial hypothalamic nucleus

subiculum

tail of embryo

median eminence

More reference expression data

BioGPS


More reference expression data

Gene ontology
Molecular function	DNA binding zinc ion binding metal ion binding DNA-binding transcription factor activity, RNA polymerase II-specific
Cellular component	nucleus cytoplasm nucleoplasm
Biological process	multicellular organism development regulation of cell morphogenesis cytoskeleton organization regulation of transcription by RNA polymerase II
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


9203


56364

Ensembl


ENSG00000147130


ENSMUSG00000031310

UniProt


Q14202


Q9JLM4

RefSeq (mRNA)


NM_001171162 NM_001171163 NM_005096 NM_201599


NM_001177985 NM_001177986 NM_001177987 NM_001177988 NM_019831

RefSeq (protein)


NP_001164633 NP_001164634 NP_005087 NP_963893


NP_001171456 NP_001171457 NP_001171458 NP_001171459 NP_062805

Location (UCSC)

Chr X: 71.24 – 71.26 Mb

Chr X: 101.4 – 101.42 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

Zinc finger MYM-type protein 3 is a protein that in humans is encoded by the ZMYM3 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000147130 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031310 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Smedley D, Hamoudi R, Lu YJ, Cooper C, Shipley J (Sep 1999). "Cloning and mapping of members of the MYM family". Genomics. 60 (2): 244–7. doi:10.1006/geno.1999.5918. PMID 10486218.
^ "Entrez Gene: ZMYM3 zinc finger, MYM-type 3".

van der Maarel SM, Scholten IH, Huber I, Philippe C, Suijkerbuijk RF, Gilgenkrantz S, Kere J, Cremers FP, Ropers HH (Jul 1996). "Cloning and characterization of DXS6673E, a candidate gene for X-linked mental retardation in Xq13.1". Human Molecular Genetics. 5 (7): 887–97. doi:10.1093/hmg/5.7.887. PMID 8817323.
Nagase T, Ishikawa K, Nakajima D, Ohira M, Seki N, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Apr 1997). "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Research. 4 (2): 141–50. doi:10.1093/dnares/4.2.141. PMID 9205841.
Scheer MP, van der Maarel S, Kübart S, Schulz A, Wirth J, Schweiger S, Ropers H, Nothwang HG (Jan 2000). "DXS6673E encodes a predominantly nuclear protein, and its mouse ortholog DXHXS6673E is alternatively spliced in a developmental- and tissue-specific manner". Genomics. 63 (1): 123–32. CiteSeerX 10.1.1.322.3999. doi:10.1006/geno.1999.6027. PMID 10662551.
Hakimi MA, Dong Y, Lane WS, Speicher DW, Shiekhattar R (Feb 2003). "A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes". The Journal of Biological Chemistry. 278 (9): 7234–9. doi:10.1074/jbc.M208992200. PMID 12493763.
Beever C, Lai BP, Baldry SE, Peñaherrera MS, Jiang R, Robinson WP, Brown CJ (Jul 2003). "Methylation of ZNF261 as an assay for determining X chromosome inactivation patterns". American Journal of Medical Genetics Part A. 120A (3): 439–41. doi:10.1002/ajmg.a.20045. PMID 12838571. S2CID 45505878.
Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP (Aug 2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the United States of America. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Cheng J, Kapranov P, Drenkow J, Dike S, Brubaker S, Patel S, Long J, Stern D, Tammana H, Helt G, Sementchenko V, Piccolboni A, Bekiranov S, Bailey DK, Ganesh M, Ghosh S, Bell I, Gerhard DS, Gingeras TR (May 2005). "Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution". Science. 308 (5725): 1149–54. Bibcode:2005Sci...308.1149C. doi:10.1126/science.1108625. PMID 15790807. S2CID 13047538.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (Nov 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.