Degradativni enzim

Degradativni enzim je enzim (u širem smislu protein) koji razgrađuje biološke molekule. Neki primeri degradativnih enzima:

  • Lipaza, razgrađuje lipide,[1]
  • Karbohidraza, razgrađuje ugljene hidrate (npr., šećere),[2]
  • Proteaza, razgrađuje proteine,[3][4]
  • Nukleaza, razgrađuje nukleinske kiseline.

Reference

  1. ↑ Svendsen A (2000). „Lipase protein engineering”. Biochim Biophys Acta 1543 (2): 223–228. DOI:10.1016/S0167-4838(00)00239-9. PMID 11150608. 
  2. ↑ „Mechanism of Carbohydrase Action”. Science 125 (3236): 12-15. 1957. DOI:10.1126/science.125.3236.12. 
  3. ↑ Barrett A.J., Rawlings ND, Woessner JF. The Handbook of Proteolytic Enzymes, 2nd ed. Academic Press, 2003. ISBN 0-12-079610-4.
  4. ↑ Hedstrom L. Serine Protease Mechanism and Specificity. Chem Rev 2002;102:4501-4523.

Literatura

  • Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X. 
  • Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036. 
  • Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0. 
  • Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097. 
  • Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X. 
  • Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842. 

Povezano

  • Hidrolaza