Indekainid
![]() | |||
(IUPAC) ime | |||
---|---|---|---|
93-[(propan-2-il)amino]propil9H-fluoren-9-karboksamid | |||
Klinički podaci | |||
AHFS/Drugs.com | Monografija | ||
Identifikatori | |||
CAS broj | 74517-78-5 | ||
ATC kod | nije dodeljen | ||
PubChem[1][2] | 52195 | ||
DrugBank | DB00192 | ||
ChemSpider[3] | 47194 | ||
Hemijski podaci | |||
Formula | C20H24N2O | ||
Mol. masa | 308.4174 | ||
SMILES | eMolekuli & PubHem | ||
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Fizički podaci | |||
Tačka topljenja | 94-95 °C (-45 °F) | ||
Farmakoinformacioni podaci | |||
Trudnoća | ? | ||
Pravni status |
Indekainid je retko korišteni antidisritmik. Indekainid deluje kao lokalni anestetik i pripada grupi antiaritmičkih agenasa koji stabilizuju membrane. On ima elektrofiziološko dejstvo karakteristično za IC klasu antiaritmika.[4][5][6]
Reference
- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
- ↑ Giardina EV, Saroff AL, Schneider M: Effect of indecainide in patients with left ventricular dysfunction. Clin Pharmacol Ther. 1990 Nov;48(5):582-9. PMID 2225716
- ↑ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”. Nucleic Acids Res. 39 (Database issue): D1035-41. PMID 21059682.
- ↑ Wishart DS, Knox C, Guo AC, Cheng D, Shrivastava S, Tzur D, Gautam B, Hassanali M (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets”. Nucleic Acids Res 36 (Database issue): D901-6. PMID 18048412.
Spoljašnje veze
![]() | Portal Medicina |
![]() | Portal Hemija |
![](http://upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/15px-Commons-logo.svg.png)
Indekainid na Wikimedijinoj ostavi
- Indecainide