Kukumizin
| Kukumizin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.21.25 | ||||||||
| CAS broj | 82062-89-3 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Kukumizin (EC 3.4.21.25, solanain, hurain, tabernamontanain) je enzim.[1][2][3][4][5][6][7] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Hidroliza proteina sa širokom specifičnošću
Ovaj enzim je izolovan iz dinje (Cucumis melo).
Reference
- ↑ Greenberg, D.M. and Winnick, T. (1940). „Plant proteases. I. Activation-inhibition reactions”. J. Biol. Chem. 135: 761-773.
- ↑ Jaffé, W.G. (1943). „Hurain, a new plant protease from Hura crepitans”. J. Biol. Chem. 149: 1-7.
- ↑ Jaffé, W.G. (1943). „A new vegetable proteolytic enzyme of the papain class”. Rev. Brasil Biol. 3: 149-157.
- ↑ Kaneda, M. and Toninaga, N. (1975). „Isolation and characterization of a proteinase from the sarcocarp of melon fruit”. J. Biochem. (Tokyo) 78: 1287-1296. PMID 5423.
- ↑ Kaneda, M., Ohmine, H., Yonezawa, H. and Tominaga, N. (1984). „Amino acid sequence around the reactive site of cucumisin from melon fruit”. J. Biochem. (Tokyo) 95: 825-829. PMID 6427203.
- ↑ Lynn, K.R. and Clevette-Radford, N.A. (1985). „Two proteases from the latex of Elaeophorbia drupifera”. Phytochemistry 24: 2843-2845.
- ↑ Kaneda, N., Minematsu, Y., Powers, J.C. and Tominaga, N. (1986). „Specificity of cucumisin in hydrolysis of peptide thiobenzyl esters”. Agric. Biol. Chem. 50: 1075-1076.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Spoljašnje veze
- MeSH Cucumisin
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
