Limonen-1,2-epoksidna hidrolaza
Limonen-1,2-epoksidna hidrolaza | |||||||||
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Identifikatori | |||||||||
EC broj | 3.3.2.8 | ||||||||
CAS broj | 216503-88-7 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Limonen-1,2-epoksidna hidrolaza (EC 3.3.2.8, limonensko oksidna hidrolaza) je enzim sa sistematskim imenom 1,2-epoksimet-8-enska hidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 1,2-epoksimeth-8-en + H2O menth-8-en-1,2-diol
Ovaj enzim učestvuje u degradaciji monoterpena kod actinobakterije Rhodococcus eritropolis.
Reference
- ↑ van der Werf, M.J., Overkamp, K.M. and de Bont, J.A.M. (1998). „Limonene-1,2-epoxide hydrolase from Rhodococcus erythropolis DCL14 belongs to a novel class of epoxide hydrolases”. J. Bacteriol. 180: 5052-5057. PMID 9748436.
- ↑ Barbirato, F., Verdoes, J.C., de Bont, J.A.M. and van der Werf, M.J. (1998). „The Rhodococcus erythropolis DCL14 limonene-1,2-epoxide hydrolase gene encodes an enzyme belonging to a novel class of epoxide hydrolases”. FEBS Lett. 438: 293-296. PMID 9827564.
- ↑ van der Werf, M.J., Swarts, H.J. and de Bont, J.A. (1999). „Rhodococcus erythropolis DCL14 contains a novel degradation pathway for limonene”. Appl. Environ. Microbiol. 65: 2092-2102. PMID 10224006.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Spoljašnje veze
- MeSH Limonene-1,2-epoxide+hydrolase
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6