N-acetilgalaktozamin-6-sulfataza
| N-acetilgalaktozamin-6-sulfataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.6.4 | ||||||||
| CAS broj | 9025-60-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
N-acetilgalaktozamin-6-sulfataza (EC 3.1.6.4, hondroitinska sulfataza, hondroitinaza, galaktoza-6-sulfatna sulfataza, acetilgalaktozamin 6-sulfataza, N-acetilgalaktozamin-6-sulfatna sulfataza, N-acetilgalaktozamin 6-sulfataza) je enzim sa sistematskim imenom N-acetil-D-galaktozamin-6-sulfat 6-sulfohidrolaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- hidroliza 6-sulfatnih grupa N-acetil-D-galaktozamin 6-sulfatnih jedinica hondroitin sulfata i D-galaktoza 6-sulfatnih jedinica keratan sulfata
Reference
- ↑ Epstein, E.H. and Leventhal, M.E. (1981). „Steroid sulfatase of human leukocytes and epidermis and the diagnosis of recessive X-linked ichthyosis”. J. Clin. Invest. 67: 1257-1262. PMID 6939689.
- ↑ Glössl, J. and Kresse, H. (1982). „Impaired degradation of keratan sulphate by Morquio A fibroblasts”. Biochem. J. 203: 335-338. PMID 6213226.
- ↑ Lim, C.T. and Horwitz, A.L. (1981). „Purification and properties of human N-acetylgalactosamine-6-sulfate sulfatase”. Biochim. Biophys. Acta 657: 344-355. PMID 7213753.
- ↑ Sørensen, S.H., Norén, O., Sjöström, H. and Danielsen, E.M. (1982). „Amphiphilic pig intestinal microvillus maltase/glucoamylase. Structure and specificity”. Eur. J. Biochem. 126: 559-568. PMID 6814909.
- ↑ Yutaka, T., Okada, S., Kato, T., Inui, K. and Yabuchi, H. (1982). „Galactose 6-sulfate sulfatase activity in Morquio syndrome”. Clin. Chim. Acta 122: 169-180. PMID 6809361.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Spoljašnje veze
- MeSH N-acetylgalactosamine-6-sulfatase
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
