Prolin-tRNK ligaza

Prolin-tRNK ligaza
Identifikatori
EC broj 6.1.1.15
CAS broj 9055-68-9
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum
Pretraga
PMC articles
PubMed articles
NCBI Protein search

Prolin-tRNK ligaza (EC 6.1.1.15, prolil-tRNK sintetaza, prolil-transferRNK sintetaza, prolil-transfer ribonukleatna sintetaza, prolinska translaza, prolil-transfer ribonukleinsko kiselinska sintetaza, prolil-s-RNK sintetaza, prolinil-tRNK ligaza) je enzim sa sistematskim imenom L-prolin:tRNKPro ligaza (formira AMP).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju

ATP + L-prolin + tRNKPro {\displaystyle \rightleftharpoons } AMP + difosfat + L-prolil-tRNKPro

Reference

  1. Norton, S.J. (1964). „Purification and properties of the prolyl RNA synthetase of Escherichia coli”. Arch. Biochem. Biophys. 106: 147-152. PMID 14217147. 
  2. Peterson, P.J. and Fowden, L. (1965). „Purification, properties and comparative specificities of the enzyme prolyl-transfer ribonucleic acid synthetase from Phaseolus aureus' and Polygonatum multiflorum. Biochem. J. 97: 112-124. PMID 16749091. 

Literatura

  • Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X. 
  • Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036. 
  • Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0. 
  • Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097. 
  • Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X. 
  • Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842. 

Spoljašnje veze

  • MeSH Proline---tRNA+ligase
  • p
  • r
  • u
TemeTipovi
EC1 Oksidoreduktaze/spisak  • EC2 Transferaze/spisak  • EC3 Hidrolaze/spisak  • EC4 Lijaze/spisak  • EC5 Izomeraze/spisak  • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6