1,4-Laktonaza

1,4-Laktonaza
Identifikatori
EC broj3.1.1.25
CAS broj37278-38-9
Baze podataka
IntEnzIntEnz pregled
BRENDABRENDA pristup
ExPASyNiceZyme pregled
KEGGKEGG pristup
MetaCycmetabolički put
PRIAMprofil
Strukture PBPRCSB PDB PDBe PDBj PDBsum
Pretraga
PMCčlanci
PubMedčlanci
NCBIproteini

1,4-Laktonaza (EC 3.1.1.25, gama-laktonaza) je enzim sa sistematskim imenom 1,4-lakton hidroksiacilhidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju

1,4-lakton + H2O {\displaystyle \rightleftharpoons } 4-hidroksikiselina

Ovaj enzim je specifičan za 1,4-laktone sa 4-8 atoma ugljenika.

Reference

  1. ^ Fishbein, W.N. & Bessman, S.P. (1966). „Purification and properties of an enzyme in human blood and rat liver microsomes catalyzing the formation and hydrolysis of γ-lactones. I. Tissue localization, stoichiometry, specificity, distinction from esterase”. J. Biol. Chem. 241: 4835—4841. PMID 4958984. 
  2. ^ Fishbein, W.N. & Bessman, S.P. (1966). „Purification and properties of an enzyme in human blood and rat liver microsomes catalyzing the formation and hydrolysis of γ-lactones. II. Metal ion effects, kinetics, and equilibria”. J. Biol. Chem. 241: 4842—4847. PMID 4958985. 

Literatura

  • Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X. 
  • Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036. 
  • Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0. 
  • Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097. 
  • William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605. 

Spoljašnje veze

  • 1,4-lactonase на US National Library of Medicine Medical Subject Headings (MeSH)
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TemeTipovi
  • B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
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