Cefetamet : Osobine, Reference, Literatura, Spoljašnje veze Википедија

Cefetamet

Cefetamet
Klinički podaci

Drugs.com	Monografija
Identifikatori
CAS broj	65052-63-3^Y
ATC kod	J01DD10 (WHO)
PubChem	CID 5487888
ChemSpider	4589562^Y
UNII	4R5TV783X3^Y
KEGG	D03424^Y
ChEMBL	CHEMBL558692^Y
Hemijski podaci
Formula	C₁₄H₁₅N₅O₅S₂
Molarna masa	397,429
SMILES CO\N=C(/C(=N/[C@H]1[C@H]2SCC(=C(N2C1=O)C(=O)O)C)/O)\C3=CSC(=N)N3
InChI InChI=1S/C14H15N5O5S2/c1-5-3-25-12-8(11(21)19(12)9(5)13(22)23)17-10(20)7(18-24-2)6-4-26-14(15)16-6/h4,8,12H,3H2,1-2H3,(H2,15,16)(H,17,20)(H,22,23)/b18-7-/t8-,12-/m1/s1^Y Key:MQLRYUCJDNBWMV-GHXIOONMSA-N^Y

Cefetamet je organsko jedinjenje, koje sadrži 14 atoma ugljenika i ima molekulsku masu od 397,429 Da.

Osobine

Osobina	Vrednost
Broj akceptora vodonika	10
Broj donora vodonika	4
Broj rotacionih veza	5
Particioni koeficijent^[1] (ALogP)	0,0
Rastvorljivost^[2] (logS, log(mol/L))	-2,0
Polarna površina^[3] (PSA, Å²)	198,3

^ Ghose, A.K.; Viswanadhan V.N. & Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A. 102: 3762—3772. doi:10.1021/jp980230o.
^ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488—1493. PMID 11749573. doi:10.1021/ci000392t.
^ Ertl P.; Rohde B.; Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714—3717. PMID 11020286. doi:10.1021/jm000942e.

Hardman JG, Limbird LE, Gilman AG (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10. изд.). New York: McGraw-Hill. ISBN 0071354697. doi:10.1036/0071422803.
Thomas L. Lemke; David A. Williams, ур. (2007). Foye's Principles of Medicinal Chemistry (6. изд.). Baltimore: Lippincott Willams & Wilkins. ISBN 0781768799.