DUTP difosfataza

DUTP difosfataza
DUTP difosfataza trimer, Human
Identifikatori
EC broj3.6.1.23
CAS broj37289-34-2
Baze podataka
IntEnzIntEnz pregled
BRENDABRENDA pristup
ExPASyNiceZyme pregled
KEGGKEGG pristup
MetaCycmetabolički put
PRIAMprofil
Strukture PBPRCSB PDB PDBe PDBj PDBsum
Pretraga
PMCčlanci
PubMedčlanci
NCBIproteini

DUTP difosfataza (EC 3.6.1.23, dezoksiuridin-trifosfataza, dUTPaza, dUTP pirofosfataza, dezoksiuridin 5'-trifosfatna nukleotidohidrolaza, desoksiuridinska 5'-trifosfataza) je enzim sa sistematskim imenom dUTP nukleotidohidrolaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju

dUTP + H2O {\displaystyle \rightleftharpoons } dUMP + difosfat

Reference

  1. ^ Bertani, L.E., Häggmark, A. and Reichard, P. (1963). „Enzymatic synthesis of deoxyribonucleotides. II. Formation and interconversion of deoxyuridine phosphates”. J. Biol. Chem. 238: 3407—3413. PMID 14085395. CS1 одржавање: Вишеструка имена: списак аутора (веза)
  2. ^ Giroir, L.E. & Deutsch, W.A. (1987). „Drosophila deoxyuridine triphosphatase. Purification and characterization”. J. Biol. Chem. 262: 130—134. PMID 3025197. 
  3. ^ Greenberg, G.R. & Somerville, R.L. (1962). „Deoxyuridylate kinase activity and deoxyuridinetriphosphatase in Escherichia coli”. Proc. Natl. Acad. Sci. USA. 48: 247—257. PMID 13901467. 
  4. ^ Grindey, G.B. & Nichol, C.A. (1971). „Mammalian deoxyuridine 5′-triphosphate pyrophosphatase”. Biochim. Biophys. Acta. 240: 180—183. PMID 5105331. 

Literatura

  • Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X. 
  • Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036. 
  • Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0. 
  • Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097. 

Spoljašnje veze

  • DUTP+diphosphatase на US National Library of Medicine Medical Subject Headings (MeSH)
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TemeTipovi
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