Galaktozilgalaktozilglukozilkeramidaza

Identifikatori

EC broj

3.2.1.47

CAS broj

2601625

Baze podataka

IntEnz

IntEnz pregled

BRENDA

BRENDA pristup

ExPASy

NiceZyme pregled

KEGG

KEGG pristup

MetaCyc

metabolički put

PRIAM

profil

Strukture PBP

RCSB PDB PDBe PDBj PDBsum

Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Galaktozilgalaktozilglukozilkeramidaza (EC 3.2.1.47, triheksozil keramid galaktozidaza, keramidna triheksozidaza, keramidtriheksozidna alfa-galaktozidaza, triheksozilkeramidna alfa-galaktozidaza, keramidtriheksozidaza) je enzim sa sistematskim imenom alfa-D-galaktozil-(1->4)-beta-D-galaktozil-(1->4)-beta-D-glukozil-(1<->1)-keramid galaktohidrolaza.^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

alfa-D-galaktozil-(1->4)-beta-D-galaktozil-(1->4)-beta-D-glukozil-(1<->1)-keramid + H₂O

\rightleftharpoons

D-galaktoza + beta-D-galaktozil-(1->4)-beta-D-glukozil-(1<->1)-keramid

Reference

^ Brady, R.O., Gal, A.E., Bradley, R.M. and Matensson, E. (1967). „The metabolism of ceramide trihexosides. I. Purification and properties of an enzyme that cleaves the terminal galactose molecule of galactosylgalactosylglucosylceramide”. J. Biol. Chem. 242: 1021—1026. PMID 6020428. CS1 одржавање: Вишеструка имена: списак аутора (веза)
^ Mapes, C.A. & Sweeley, C.C. (1972). „Substrate specificity of ceramide trihexosidase”. FEBS Lett. 25: 279—281. PMID 11946769.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

Galactosylgalactosylglucosylceramidase на US National Library of Medicine Medical Subject Headings (MeSH)

Enzimi

Teme

Tipovi

EC1 Oksidoreduktaze /spisak
EC2 Transferaze /spisak
EC3 Hidrolaze /spisak
EC4 Lijaze /spisak
EC5 Izomeraze /spisak
EC6 Ligaze /spisak

B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6