Histolizain
| Histolizain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.22.35 | ||||||||
| CAS broj | 92228-52-9 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Histolizain (EC 3.4.22.35, histolizin, histolizin, Entamoeba histolytica cisteinska proteinaza, amebapain, Entamoeba histolytica cisteinska proteaza, Entamoeba histolytica neutralna tiolna proteinaza) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Hidroliza proteina, uključujući membranski kolagen i azokasein. Preferentno razlaganje: Arg-Arg- u malim molekulima uključujući Z-Arg-Arg-NHMec
Ovaj enzim je prisutan u protozoi, Entamoeba histolytica.
Reference
- ^ Lushbaugh, W.B., Hofbauer, A.F. and Pittman, F.E. (1985). „Entamoeba histolytica: purification of cathepsin B”. Exp. Parasitol. 59: 328—336. PMID 2860002. CS1 одржавање: Вишеструка имена: списак аутора (веза)
- ^ Luaces, A.L. & Barrett, A.J. (1988). „Affinity purification and biochemical characterization of histolysin: the major cysteine proteinase of Entamoeba histolytica”. Biochem. J. 250: 903—909. PMID 2898937.
Literatura
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
- Histolysain на US National Library of Medicine Medical Subject Headings (MeSH)
- п
- р
- у
- EC1 Oksidoreduktaze /spisak
- EC2 Transferaze /spisak
- EC3 Hidrolaze /spisak
- EC4 Lijaze /spisak
- EC5 Izomeraze /spisak
- EC6 Ligaze /spisak
- B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
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