Poliribonukleotid nukleotidiltransferaza

Poliribonukleotid nukleotidiltransferaza
Identifikatori
EC broj2.7.7.8
CAS broj2598674
Baze podataka
IntEnzIntEnz pregled
BRENDABRENDA pristup
ExPASyNiceZyme pregled
KEGGKEGG pristup
MetaCycmetabolički put
PRIAMprofil
Strukture PBPRCSB PDB PDBe PDBj PDBsum
Pretraga
PMCčlanci
PubMedčlanci
NCBIproteini

Poliribonukleotid nukleotidiltransferaza (EC 2.7.7.8, polinukleotidna fosforilaza, PNPaza, nukleozid difosfat:polinukleotidil transferaza, poliribonukleotidna nukleotidiltransferaza, polinukleotidna fosforilaza, poliribonukleotidna fosforilaza) je enzim sa sistematskim imenom poliribonukleotid:fosfat nucleotidiltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

RNKn+1 + fosfat {\displaystyle \rightleftharpoons } RNKn + nukleozid difosfat

ADP, IDP, GDP, UDP i CDP mogu da deluju kao donori.

Reference

  1. ^ Hakim, A.A. (1959). „Synthetic activity of polynucleotide phosphorylase from sperm”. Nature. 183: 334—334. PMID 13632712. 
  2. ^ Littauer, U.Z. & Kornberg, A. (1957). „Reversible synthesis of polyribonucleotides with an enzyme from Escherichia coli”. J. Biol. Chem. 226: 1077—1092. PMID 13438894. 
  3. ^ Ochoa, S. & Mii, S. (1961). „Enzymatic synthesis of polynucleotides. IV. Purification and properties of polynucleotide phosphorylase from Azotobacter vinelandii”. J. Biol. Chem. 236: 3303—3311. PMID 14481058. 

Literatura

  • Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X. 
  • Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036. 
  • Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0. 
  • Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097. 
  • William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605. 

Spoljašnje veze

  • Polyribonucleotide+nucleotidyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
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TemeTipovi
  • B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
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