UMP kinaza
UMP kinaza | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifikatori | |||||||||
EC broj | 2.7.4.22 | ||||||||
CAS broj | 9036-23-1 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
|
UMP kinaza (EC 2.7.4.22, uridilatba kinaza, UMPK, uridin monofosfatna kinaza, PyrH, UMP-kinaza, SmbA) je enzim sa sistematskim imenom ATP:UMP fosfotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ovaj enzim je striktno specifičan za UMP kao supstrat.
Reference
- ^ Serina, L., Blondin, C., Krin, E., Sismeiro, O., Danchin, A., Sakamoto, H., Gilles, A.M. and Bârzu, O. (1995). „Escherichia coli UMP-kinase, a member of the aspartokinase family, is a hexamer regulated by guanine nucleotides and UTP”. Biochemistry. 34: 5066—5074. PMID 7711027. CS1 одржавање: Вишеструка имена: списак аутора (веза)
- ^ Marco-Marín, C., Gil-Ortiz, F. and Rubio, V. (2005). „The crystal structure of Pyrococcus furiosus UMP kinase provides insight into catalysis and regulation in microbial pyrimidine nucleotide biosynthesis”. J. Mol. Biol. 352: 438—454. PMID 16095620. CS1 одржавање: Вишеструка имена: списак аутора (веза)
Literatura
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
- UMP+kinase на US National Library of Medicine Medical Subject Headings (MeSH)
- п
- р
- у
- EC1 Oksidoreduktaze /spisak
- EC2 Transferaze /spisak
- EC3 Hidrolaze /spisak
- EC4 Lijaze /spisak
- EC5 Izomeraze /spisak
- EC6 Ligaze /spisak
- B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6