CYP46A1 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/b/b2/Protein_CYP46A1_PDB_2Q9F.png/250px-Protein_CYP46A1_PDB_2Q9F.png) |
已知的結構 |
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PDB | 直系同源搜索: PDBe RCSB |
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PDBID列表 |
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4FIA、2Q9F、3MDV、4J14、4ENH、2Q9G、3MDM、3MDT、3MDR |
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識別號 |
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别名 | CYP46A1;, CP46, CYP46, cytochrome P450 family 46 subfamily A member 1 |
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外部ID | OMIM:604087 MGI:1341877 HomoloGene:134501 GeneCards:CYP46A1 |
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基因位置(小鼠) |
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![小鼠12号染色体](//upload.wikimedia.org/wikipedia/commons/thumb/c/ca/Ideogram_house_mouse_chromosome_12.svg/260px-Ideogram_house_mouse_chromosome_12.svg.png) | 染色体 | 小鼠12号染色体[2] |
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| 基因座 | 12|12 F1 | 起始 | 108,300,640 bp[2] |
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终止 | 108,328,493 bp[2] |
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RNA表达模式 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/9/96/PBB_GE_CYP46A1_220331_at_fs.png/250px-PBB_GE_CYP46A1_220331_at_fs.png) |
查阅更多表达数据 |
基因本體 |
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分子功能 | • iron ion binding • 金屬離子結合 • monooxygenase activity • steroid hydroxylase activity • heme binding • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen • oxidoreductase activity • cholesterol 24-hydroxylase activity
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細胞組分 | • organelle membrane • integral component of membrane • endoplasmic reticulum membrane • 膜 • 細胞內膜結合細胞器 • 内质网 • 树突 • presynapse • postsynapse • 细胞连接 • cell projection • 突触
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生物學過程 | • steroid metabolic process • 脂質代謝 • cholesterol metabolic process • cholesterol catabolic process • 神經系統的發育 • sterol metabolic process • bile acid biosynthetic process • xenobiotic metabolic process • progesterone metabolic process • regulation of long-term synaptic potentiation • C21-steroid hormone metabolic process
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Sources:Amigo / QuickGO |
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直系同源 |
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物種 | 人類 | 小鼠 |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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mRNA序列 | | |
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蛋白序列 | | |
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基因位置(UCSC) | Chr 14: 99.68 – 99.73 Mb | Chr 12: 108.3 – 108.33 Mb |
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PubMed查找 | [3] | [4] |
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維基數據 |
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