HDAC1
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Àlies | HDAC1 (HUGO), GON-10, HD1, RPD3, RPD3L1, histone deacetylase 1, KDAC1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
IDs externes | OMIM: 601241 MGI: 108086 HomoloGene: 68426 GeneCards: HDAC1 OMA: HDAC1 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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La histona deacetilasa 1 (HDAC1) és un enzim codificat en humans pel gen HDAC1.[5]
Funció
Les histones tenen un paper crucial en la regulació de la transcripció, en la progressió del cicle cel·lular i en processos de desenvolupament. La acetilació/desacetilació d'histones altera l'estructura del cromosoma, variant així l'accessibilitat dels factors de transcripció a l'ADN. La HDAC1 pertany a la família d'histona deacetilases acuc/alfa i és un dels components del complex histona deacetilasa. Aquesta proteïna interacciona amb la proteïna del retinoblastoma formant un complex que constitueix un element clau en el control de la proliferació cel·lular i la diferenciació cel·lular. Juntament amb la proteïna 2 associada a metàstasi, deacetila a p53 i modula la seva acció sobre la proliferació cel·lular i l'apoptosi.[6]
Interaccions
La histona deacetilasa 1 ha demostrat ser capaç d'interaccionar amb:
- RAD9A[7]
- DNMT3L[8][9]
- MTA1[10][11]
- FKBP3[12]
- CDC20[13]
- CDH1[13]
- HCFC1[14]
- BUB3[13]
- NCOR2[15][16]
- IKZF1[17][18]
- Prohibitina[19][20]
- EVI1[21][22]
- DDX5[23]
- DNMT3A[24]
- SMAD2[25]
- HDAC2[26][10][27][28][29][30][15][31][32][33][34][35][36]
- MIER1[37]
- SIN3A[38][10][39][40][41][42][43][32][44][33][34][45][46][47]
- Proteína 6 associada a mort[48]
- Receptor androgènic[49]
- HMG20B[26]
- HUS1[7]
- IFRD1[50]
- MLL[51]
- ING1[52][47]
- MyoD[53][54]
- GATA1[55]
- SPEN[56]
- MAD1L1[13]
- Proteïna de la leucèmia promielocítica[57][58]
- CHD3[33][47]
- TGIF1[59][60]
- Proteïna del retinoblastoma-like 2[61][62]
- Proteïna del retinoblastoma-like 1[63][61]
- CHD4[10][41][33]
- RCOR1[26][43]
- RBBP7[10][64][32][35]
- RFC1[65]
- Proteïna del retinoblastoma[66][67][53][20][68][63][61]
- RBBP4[38][10][69][41][43][70][64][32][44][34][35]
- EED[36]
- PHF21A[26][71]
- SIN3B[32][17]
- RELA[72][73][31]
- NFKB1[73]
- BUB1B[13]
- Mdm2[74]
- SATB1[45]
- HSPA4[29]
- SUV39H1[75]
- BUB1[13]
- MBD2[76][64][32]
- ZBTB16[77][78][79]
- DDX17[23]
- BCL6[78][80]
- SUDS3[39][81]
- SAP30[82][83][32][84][85][47]
- Sp1[86][87][44][88]
- MTA2[10][43][32][45]
- PCNA[89]
- CBFA2T3[90][91]
- TOP2B[92][93]
- MBD3[94][32][95]
- CTBP1[96][59][97]
- TOP2A[92][93]
- EZH2[36]
- COUP-TFII[98]
Referències
- ↑ 1,0 1,1 1,2 GRCh38: Ensembl release 89: ENSG00000116478 - Ensembl, May 2017
- ↑ 2,0 2,1 2,2 GRCm38: Ensembl release 89: ENSMUSG00000028800 – Ensembl, May 2017
- ↑ «Human PubMed Reference:». National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ «Mouse PubMed Reference:». National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ Taunton J, Hassig CA, Schreiber SL «A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p». Science, 272, 5260, May 1996, pàg. 408–11. PMID: 8602529.
- ↑ «Entrez Gene: HDAC1 histone deacetylase 1».
- ↑ 7,0 7,1 Cai, R L; Yan-Neale Y, Cueto M A, Xu H, Cohen D «HDAC1, a histone deacetylase, forms a complex with Hus1 and Rad9, two G2/M checkpoint Rad proteins». J. Biol. Chem. [UNITED STATES], 275, 36, Sep. 2000, pàg. 27909–16. DOI: 10.1074/jbc.M000168200. ISSN: 0021-9258. PMID: 10846170.
- ↑ Aapola, Ulla; Liiv Ingrid, Peterson Pärt «Imprinting regulator DNMT3L is a transcriptional repressor associated with histone deacetylase activity». Nucleic Acids Res. [England], 30, 16, Aug. 2002, pàg. 3602–8. PMID: 12177302.
- ↑ Deplus, Rachel; Brenner Carmen, Burgers Wendy A, Putmans Pascale, Kouzarides Tony, de Launoit Yvan, Fuks François «Dnmt3L is a transcriptional repressor that recruits histone deacetylase». Nucleic Acids Res. [England], 30, 17, Sep. 2002, pàg. 3831–8. PMID: 12202768.
- ↑ 10,0 10,1 10,2 10,3 10,4 10,5 10,6 Yao, Ya-Li; Yang Wen-Ming «The metastasis-associated proteins 1 and 2 form distinct protein complexes with histone deacetylase activity». J. Biol. Chem. [United States], 278, 43, Oct. 2003, pàg. 42560–8. DOI: 10.1074/jbc.M302955200. ISSN: 0021-9258. PMID: 12920132.
- ↑ Mazumdar, A; Wang R A, Mishra S K, Adam L, Bagheri-Yarmand R, Mandal M, Vadlamudi R K, Kumar R «Transcriptional repression of oestrogen receptor by metastasis-associated protein 1 correpressor». Nat. Cell Biol. [England], 3, 1, Jan. 2001, pàg. 30–7. DOI: 10.1038/35050532. ISSN: 1465-7392. PMID: 11146623.
- ↑ Yang, W M; Yao Y L, Seto E «The FK506-binding protein 25 functionally associates with histone deacetylases and with transcription factor YY1». EMBO J. [England], 20, 17, Sep. 2001, pàg. 4814–25. DOI: 10.1093/emboj/20.17.4814. ISSN: 0261-4189. PMID: 11532945.
- ↑ 13,0 13,1 13,2 13,3 13,4 13,5 Yoon, Young-Mee; Baek Kwan-Hyuck, Jeong Sook-Jung, Shin Hyun-Jin, Ha Geun-Hyoung, Jeon Ae-Hwa, Hwang Sang-Gu, Chun Jang-Soo, Lee Chang-Woo «WD repeat-containing mitotic checkpoint proteins act as transcriptional repressors during interphase». FEBS Lett. [Netherlands], 575, 1-3, Sep. 2004, pàg. 23–9. DOI: 10.1016/j.febslet.2004.07.089. ISSN: 0014-5793. PMID: 15388328.
- ↑ Wysocka, Joanna; Myers Michael P, Laherty Carol D, Eisenman Robert N, Herr Winship «Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1». Genes Dev. [United States], 17, 7, Apr. 2003, pàg. 896–911. DOI: 10.1101/gad.252103. ISSN: 0890-9369. PMID: 12670868.
- ↑ 15,0 15,1 Fischer, Denise D; Cai Richard, Bhatia Umesh, Asselbergs Fred A M, Song Chuanzheng, Terry Robert, Trogani Nancy, Widmer Roland, Atadja Peter, Cohen Dalia «Isolation and characterization of a novel class II histone deacetylase, HDAC10». J. Biol. Chem. [United States], 277, 8, Feb. 2002, pàg. 6656–66. DOI: 10.1074/jbc.M108055200. ISSN: 0021-9258. PMID: 11739383.
- ↑ Underhill, C; Qutob M S, Yee S P, Torchia J «A novel nuclear receptor correpressor complex, N-CoR, contains components of the mammalian SWI/SNF complex and the correpressor KAP-1». J. Biol. Chem. [UNITED STATES], 275, 51, Dec. 2000, pàg. 40463–70. DOI: 10.1074/jbc.M007864200. ISSN: 0021-9258. PMID: 11013263.
- ↑ 17,0 17,1 Koipally, J; Renold A; Kim J; Georgopoulos K «Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes». EMBO J. [ENGLAND], 18, 11, Jun. 1999, pàg. 3090–100. DOI: 10.1093/emboj/18.11.3090. ISSN: 0261-4189. PMID: 10357820.
- ↑ Koipally, Joseph; Georgopoulos Katia «A molecular dissection of the repression circuitry of Ikaros». J. Biol. Chem. [United States], 277, 31, Aug. 2002, pàg. 27697–705. DOI: 10.1074/jbc.M201694200. ISSN: 0021-9258. PMID: 12015313.
- ↑ Joshi, Bharat; Ko Danette, Ordonez-Ercan Dalia, Chellappan Srikumar P «A putative coiled-coil domain of prohibitin is sufficient to repress E2F1-mediated transcription and induce apoptosis». Biochem. Biophys. Res. Commun. [United States], 312, 2, Dec. 2003, pàg. 459–66. ISSN: 0006-291X. PMID: 14637159.
- ↑ 20,0 20,1 Wang, Sheng; Fusaro Gina, Padmanabhan Jaya, Chellappan Srikumar P «Prohibitin co-localizes with Rb in the nucleus and recruits N-CoR and HDAC1 for transcriptional repression». Oncogene [England], 21, 55, Dec. 2002, pàg. 8388–96. DOI: 10.1038/sj.onc.1205944. ISSN: 0950-9232. PMID: 12466959.
- ↑ Vinatzer, U; Taplick J; Seiser C; Fonatsch C; Wieser R «The leukaemia-associated transcription factors EVI-1 and MDS1/EVI1 repress transcription and interact with histone deacetylase». Br. J. Haematol. [England], 114, 3, Sep. 2001, pàg. 566–73. ISSN: 0007-1048. PMID: 11552981.
- ↑ Chakraborty, S; Senyuk V; Sitailo S; Chi Y; Nucifora G «Interaction of EVI1 with cAMP-responsive element-binding protein-binding protein (CBP) and p300/CBP-associated factor (P/CAF) results in reversible acetylation of EVI1 and in co-localization in nuclear speckles». J. Biol. Chem. [United States], 276, 48, Nov. 2001, pàg. 44936–43. DOI: 10.1074/jbc.M106733200. ISSN: 0021-9258. PMID: 11568182.
- ↑ 23,0 23,1 Wilson, Brian J; Bates Gaynor J, Nicol Samantha M, Gregory David J, Perkins Neil D, Fuller-Pace Frances V «The p68 and p72 DEAD box RNA helicases interact with HDAC1 and repress transcription in a promoter-specific manner». BMC Mol. Biol. [England], 5, Aug. 2004, pàg. 11. DOI: 10.1186/1471-2199-5-11. PMID: 15298701.
- ↑ Fuks, F; Burgers W A, Godin N, Kasai M, Kouzarides T «Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription». EMBO J. [England], 20, 10, maig. 2001, pàg. 2536–44. DOI: 10.1093/emboj/20.10.2536. ISSN: 0261-4189. PMID: 11350943.
- ↑ Wotton, D; Lo R S, Lee S, Massagué J «A Smad transcriptional correpressor». Cell [UNITED STATES], 97, 1, Apr. 1999, pàg. 29–39. ISSN: 0092-8674. PMID: 10199400.
- ↑ 26,0 26,1 26,2 26,3 Hakimi, Mohamed-Ali; Bochar Daniel A, Chenoweth Josh, Lane William S, Mandel Gail, Shiekhattar Ramin «A core-BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes». Proc. Natl. Acad. Sci. U.S.A. [United States], 99, 11, maig. 2002, pàg. 7420–5. DOI: 10.1073/pnas.112008599. ISSN: 0027-8424. PMID: 12032298.
- ↑ Hakimi, Mohamed-Ali; Dong Yuanshu, Lane William S, Speicher David W, Shiekhattar Ramin «A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes». J. Biol. Chem. [United States], 278, 9, Feb. 2003, pàg. 7234–9. DOI: 10.1074/jbc.M208992200. ISSN: 0021-9258. PMID: 12493763.
- ↑ Fischle, Wolfgang; Dequiedt Franck, Hendzel Michael J, Guenther Matthew G, Lazar Mitchell A, Voelter Wolfgang, Verdin Eric «Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR». Mol. Cell [United States], 9, 1, Jan. 2002, pàg. 45–57. ISSN: 1097-2765. PMID: 11804585.
- ↑ 29,0 29,1 Johnson, Colin A; White Darren A, Lavender Jayne S, O'Neill Laura P, Turner Bryan M «Human class I histone deacetylase complexes show enhanced catalytic activity in the presence of ATP and co-immunoprecipitate with the ATP-dependent chaperone protein Hsp70». J. Biol. Chem. [United States], 277, 11, Mar. 2002, pàg. 9590–7. DOI: 10.1074/jbc.M107942200. ISSN: 0021-9258. PMID: 11777905.
- ↑ Fischle, W; Dequiedt F, Fillion M, Hendzel M J, Voelter W, Verdin E «Human HDAC7 histone deacetylase activity is associated with HDAC3 in vivo». J. Biol. Chem. [United States], 276, 38, Sep. 2001, pàg. 35826–35. DOI: 10.1074/jbc.M104935200. ISSN: 0021-9258. PMID: 11466315.
- ↑ 31,0 31,1 Ashburner, B P; Westerheide S D, Baldwin A S «The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) correpressors HDAC1 and HDAC2 to negatively regulate gene expression». Mol. Cell. Biol. [United States], 21, 20, Oct. 2001, pàg. 7065–77. DOI: 10.1128/MCB.21.20.7065-7077.2001. ISSN: 0270-7306. PMID: 11564889.
- ↑ 32,0 32,1 32,2 32,3 32,4 32,5 32,6 32,7 32,8 Zhang, Y; Ng H H, Erdjument-Bromage H, Tempst P, Bird A, Reinberg D «Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation». Genes Dev. [UNITED STATES], 13, 15, Aug. 1999, pàg. 1924–35. ISSN: 0890-9369. PMID: 10444591.
- ↑ 33,0 33,1 33,2 33,3 Tong, J K; Hassig C A, Schnitzler G R, Kingston R E, Schreiber S L «Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex». Nature [ENGLAND], 395, 6705, Oct. 1998, pàg. 917–21. DOI: 10.1038/27699. ISSN: 0028-0836. PMID: 9804427.
- ↑ 34,0 34,1 34,2 Hassig, C A; Tong J K, Fleischer T C, Owa T, Grable P G, Ayer D E, Schreiber S L «A role for histone deacetylase activity in HDAC1-mediated transcriptional repression». Proc. Natl. Acad. Sci. U.S.A. [UNITED STATES], 95, 7, Mar. 1998, pàg. 3519–24. ISSN: 0027-8424. PMID: 9520398.
- ↑ 35,0 35,1 35,2 Zhang, Y; Iratni R, Erdjument-Bromage H, Tempst P, Reinberg D «Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex». Cell [UNITED STATES], 89, 3, maig. 1997, pàg. 357–64. ISSN: 0092-8674. PMID: 9150135.
- ↑ 36,0 36,1 36,2 van der Vlag, J; Otte A P «Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation». Nat. Genet. [UNITED STATES], 23, 4, Dec. 1999, pàg. 474–8. DOI: 10.1038/70602. ISSN: 1061-4036. PMID: 10581039.
- ↑ Ding, Zhihu; Gillespie Laura L, Paterno Gary D «Human MI-ER1 alpha and beta function as transcriptional repressors by recruitment of histone deacetylase 1 to their conserved ELM2 domain». Mol. Cell. Biol. [United States], 23, 1, Jan. 2003, pàg. 250–8. ISSN: 0270-7306. PMID: 12482978.
- ↑ 38,0 38,1 Zhang, Ying; Dufau Maria L «Dual mechanisms of regulation of transcription of luteinizing hormone receptor gene by nuclear orphan receptors and histone deacetylase complexes». J. Steroid Biochem. Mol. Biol. [England], 85, 2-5, Jun. 2003, pàg. 401–14. ISSN: 0960-0760. PMID: 12943729.
- ↑ 39,0 39,1 Fleischer, Tracey C; Yun Ui Jeong, Ayer Donald E «Identification and characterization of three new components of the mSin3A correpressor complex». Mol. Cell. Biol. [United States], 23, 10, maig. 2003, pàg. 3456–67. ISSN: 0270-7306. PMID: 12724404.
- ↑ Yang, Liu; Mei Qi, Zielinska-Kwiatkowska Anna, Matsui Yoshito, Blackburn Michael L, Benedetti Daniel, Krumm Anton A, Taborsky Gerald J, Chansky Howard A «An ERG (ets-related gene)-associated histone methyltransferase interacts with histone deacetylases 1/2 and transcription co-repressors mSin3A/B». Biochem. J. [England], 369, Pt 3, Feb. 2003, pàg. 651–7. DOI: 10.1042/BJ20020854. ISSN: 0264-6021. PMID: 12398767.
- ↑ 41,0 41,1 41,2 Grozinger, C M; Hassig C A, Schreiber S L «Three proteins define a class of human histone deacetylases related to yeast Hda1p». Proc. Natl. Acad. Sci. U.S.A. [UNITED STATES], 96, 9, Apr. 1999, pàg. 4868–73. ISSN: 0027-8424. PMID: 10220385.
- ↑ Zhang, Jinsong; Kalkum Markus, Chait Brian T, Roeder Robert G «The N-CoR-HDAC3 nuclear receptor correpressor complex inhibits the JNK pathway through the integral subunit GPS2». Mol. Cell [United States], 9, 3, Mar. 2002, pàg. 611–23. ISSN: 1097-2765. PMID: 11931768.
- ↑ 43,0 43,1 43,2 43,3 You, A; Tong J K, Grozinger C M, Schreiber S L «CoREST is an integral component of the CoREST- human histone deacetylase complex». Proc. Natl. Acad. Sci. U.S.A. [United States], 98, 4, Feb. 2001, pàg. 1454–8. DOI: 10.1073/pnas.98.4.1454. ISSN: 0027-8424. PMID: 11171972.
- ↑ 44,0 44,1 44,2 Zhang, Ying; Dufau Maria L «Silencing of transcription of the human luteinizing hormone receptor gene by histone deacetylase-mSin3A complex». J. Biol. Chem. [United States], 277, 36, Sep. 2002, pàg. 33431–8. DOI: 10.1074/jbc.M204417200. ISSN: 0021-9258. PMID: 12091390.
- ↑ 45,0 45,1 45,2 Yasui, Dag; Miyano Masaru, Cai Shutao, Varga-Weisz Patrick, Kohwi-Shigematsu Terumi «SATB1 targets chromatin remodelling to regulate genes over long distances». Nature [England], 419, 6907, Oct. 2002, pàg. 641–5. DOI: 10.1038/nature01084. ISSN: 0028-0836. PMID: 12374985.
- ↑ Huang, E Y; Zhang J, Miska E A, Guenther M G, Kouzarides T, Lazar M A «Nuclear receptor correpressors partner with class II histone deacetylases in a Sin3-independent repression pathway». Genes Dev. [UNITED STATES], 14, 1, Jan. 2000, pàg. 45–54. ISSN: 0890-9369. PMID: 10640275.
- ↑ 47,0 47,1 47,2 47,3 Kuzmichev, A; Zhang Y, Erdjument-Bromage H, Tempst P, Reinberg D «Role of the Sin3-histone deacetylase complex in growth regulation by the candidate tumor suppressor p33(ING1)». Mol. Cell. Biol. [United States], 22, 3, Feb. 2002, pàg. 835–48. ISSN: 0270-7306. PMID: 11784859.
- ↑ Li, H; Leo C, Zhu J, Wu X, O'Neil J, Park E J, Chen J D «Sequestration and inhibition of Daxx-mediated transcriptional repression by PML». Mol. Cell. Biol. [UNITED STATES], 20, 5, Mar. 2000, pàg. 1784–96. ISSN: 0270-7306. PMID: 10669754.
- ↑ Gaughan, Luke; Logan Ian R, Cook Susan, Neal David E, Robson Craig N «Tip60 and histone deacetylase 1 regulate androgen receptor activity through changes to the acetylation status of the receptor». J. Biol. Chem. [United States], 277, 29, Jul. 2002, pàg. 25904–13. DOI: 10.1074/jbc.M203423200. ISSN: 0021-9258. PMID: 11994312.
- ↑ Vietor, Ilja; Vadivelu Santhosh K, Wick Nikolaus, Hoffman Robert, Cotten Matt, Seiser Christian, Fialka Irene, Wunderlich Winfried, Haase Astrid, Korinkova Gabriela, Brosch Gerald, Huber Lukas A «TIS7 interacts with the mammalian SIN3 histone deacetylase complex in epithelial cells». EMBO J. [England], 21, 17, Sep. 2002, pàg. 4621–31. ISSN: 0261-4189. PMID: 12198164.
- ↑ Xia, Zhen-Biao; Anderson Melanie, Diaz Manuel O, Zeleznik-Le Nancy J «MLL repression domain interacts with histone deacetylases, the polycomb group proteins HPC2 and BMI-1, and the correpressor C-terminal-binding protein». Proc. Natl. Acad. Sci. U.S.A. [United States], 100, 14, Jul. 2003, pàg. 8342–7. DOI: 10.1073/pnas.1436338100. ISSN: 0027-8424. PMID: 12829790.
- ↑ Vieyra, Diego; Loewith Robbie, Scott Michelle, Bonnefin Paul, Boisvert Francois-Michel, Cheema Parneet, Pastyryeva Svitlana, Meijer Maria, Johnston Randal N, Bazett-Jones David P, McMahon Steven, Cole Michael D, Young Dallan, Riabowol Karl «Human ING1 proteins differentially regulate histone acetylation». J. Biol. Chem. [United States], 277, 33, Aug. 2002, pàg. 29832–9. DOI: 10.1074/jbc.M200197200. ISSN: 0021-9258. PMID: 12015309.
- ↑ 53,0 53,1 Puri, P L; Iezzi S, Stiegler P, Chen T T, Schiltz R L, Muscat G E, Giordano A, Kedes L, Wang J Y, Sartorelli V «Class I histone deacetylases sequentially interact with MyoD and pRb during skeletal myogenesis». Mol. Cell [United States], 8, 4, Oct. 2001, pàg. 885–97. ISSN: 1097-2765. PMID: 11684023.
- ↑ Mal, A; Sturniolo M, Schiltz R L, Ghosh M K, Harter M L «A role for histone deacetylase HDAC1 in modulating the transcriptional activity of MyoD: inhibition of the myogenic program». EMBO J. [England], 20, 7, Apr. 2001, pàg. 1739–53. DOI: 10.1093/emboj/20.7.1739. ISSN: 0261-4189. PMID: 11285237.
- ↑ Watamoto, Kouichi; Towatari Masayuki, Ozawa Yukiyasu, Miyata Yasuhiko, Okamoto Mitsunori, Abe Akihiro, Naoe Tomoki, Saito Hidehiko «Altered interaction of HDAC5 with GATA-1 during MEL cell differentiation». Oncogene [England], 22, 57, Dec. 2003, pàg. 9176–84. DOI: 10.1038/sj.onc.1206902. ISSN: 0950-9232. PMID: 14668799.
- ↑ Shi, Y; Downes M, Xie W, Kao H Y, Ordentlich P, Tsai C C, Hon M, Evans R M «Sharp, an inducible cofactor that integrates nuclear receptor repression and activation». Genes Dev. [United States], 15, 9, maig. 2001, pàg. 1140–51. DOI: 10.1101/gad.871201. ISSN: 0890-9369. PMID: 11331609.
- ↑ Khan, M M; Nomura T, Kim H, Kaul S C, Wadhwa R, Shinagawa T, Ichikawa-Iwata E, Zhong S, Pandolfi P P, Ishii S «Role of PML and PML-RARalpha in Mad-mediated transcriptional repression». Mol. Cell [United States], 7, 6, Jun. 2001, pàg. 1233–43. ISSN: 1097-2765. PMID: 11430826.
- ↑ Wu, W S; Vallian S, Seto E, Yang W M, Edmondson D, Roth S, Chang K S «The growth suppressor PML represses transcription by functionally and physically interacting with histone deacetylases». Mol. Cell. Biol. [United States], 21, 7, Apr. 2001, pàg. 2259–68. DOI: 10.1128/MCB.21.7.2259-2268.2001. ISSN: 0270-7306. PMID: 11259576.
- ↑ 59,0 59,1 Melhuish, T A; Wotton D «The interaction of the carboxyl terminus-binding protein with the Smad correpressor TGIF is disrupted by a holoprosencephaly mutation in TGIF». J. Biol. Chem. [UNITED STATES], 275, 50, Dec. 2000, pàg. 39762–6. DOI: 10.1074/jbc.C000416200. ISSN: 0021-9258. PMID: 10995736.
- ↑ Melhuish, T A; Gallo C M, Wotton D «TGIF2 interacts with histone deacetylase 1 and represses transcription». J. Biol. Chem. [United States], 276, 34, Aug. 2001, pàg. 32109–14. DOI: 10.1074/jbc.M103377200. ISSN: 0021-9258. PMID: 11427533.
- ↑ 61,0 61,1 61,2 Ferreira, R; Magnaghi-Jaulin L, Robin P, Harel-Bellan A, Trouche D «The three members of the pocket proteins family share the ability to repress E2F activity through recruitment of a histone deacetylase». Proc. Natl. Acad. Sci. U.S.A. [UNITED STATES], 95, 18, Sep. 1998, pàg. 10493–8. ISSN: 0027-8424. PMID: 9724731.
- ↑ Bouzahzah, B; Fu M, Iavarone A, Factor V M, Thorgeirsson S S, Pestell R G «Transforming growth factor-beta1 recruits histone deacetylase 1 to a p130 repressor complex in transgenic mice in vivo». Cancer Res. [UNITED STATES], 60, 16, Aug. 2000, pàg. 4531–7. ISSN: 0008-5472. PMID: 10969803.
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- ↑ Di Padova, Monica; Bruno Tiziana, De Nicola Francesca, Iezzi Simona, D'Angelo Carmen, Gallo Rita, Nicosia Daniela, Corbi Nicoletta, Biroccio Annamaria, Floridi Aristide, Passananti Claudio, Fanciulli Maurizio «Che-1 arrests human colon carcinoma cell proliferation by displacing HDAC1 from the p21WAF1/CIP1 promoter». J. Biol. Chem. [United States], 278, 38, Sep. 2003, pàg. 36496–504. DOI: 10.1074/jbc.M306694200. ISSN: 0021-9258. PMID: 12847090.
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- ↑ Hoogeveen, André T; Rossetti Stefano, Stoyanova Violeta, Schonkeren Joris, Fenaroli Angelia, Schiaffonati Luisa, van Unen Leontine, Sacchi Nicoletta «The transcriptional correpressor MTG16a contains a novel nucleolar targeting sequence deranged in t (16; 21)-positive myeloid malignancies». Oncogene [England], 21, 43, Sep. 2002, pàg. 6703–12. DOI: 10.1038/sj.onc.1205882. ISSN: 0950-9232. PMID: 12242670.
- ↑ Amann, J M; Nip J, Strom D K, Lutterbach B, Harada H, Lenny N, Downing J R, Meyers S, Hiebert S W «ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain». Mol. Cell. Biol. [United States], 21, 19, Oct. 2001, pàg. 6470–83. ISSN: 0270-7306. PMID: 11533236.
- ↑ 92,0 92,1 Tsai, S C; Valkov N, Yang W M, Gump J, Sullivan D, Seto E «Histone deacetylase interacts directly with DNA topoisomerase II». Nat. Genet. [UNITED STATES], 26, 3, Nov. 2000, pàg. 349–53. DOI: 10.1038/81671. ISSN: 1061-4036. PMID: 11062478.
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- ↑ Sakai, Hirotaka; Urano Takeshi, Ookata Kayoko, Kim Mi-Hyun, Hirai Yugo, Saito Motoki, Nojima Yoshihisa, Ishikawa Fuyuki «MBD3 and HDAC1, two components of the NuRD complex, are localized at Aurora-A-positive centrosomes in M phase». J. Biol. Chem. [United States], 277, 50, Dec. 2002, pàg. 48714–23. DOI: 10.1074/jbc.M208461200. ISSN: 0021-9258. PMID: 12354758.
- ↑ Saito, Motoki; Ishikawa Fuyuki «The mCpG-binding domain of human MBD3 does not bind to mCpG but interacts with NuRD/Mi2 components HDAC1 and MTA2». J. Biol. Chem. [United States], 277, 38, Sep. 2002, pàg. 35434–9. DOI: 10.1074/jbc.M203455200. ISSN: 0021-9258. PMID: 12124384.
- ↑ Zhang, C L; McKinsey T A, Lu J R, Olson E N «Association of COOH-terminal-binding protein (CtBP) and MEF2-interacting transcription repressor (MITR) contributes to transcriptional repression of the MEF2 transcription factor». J. Biol. Chem. [UNITED STATES], 276, 1, Jan. 2001, pàg. 35–9. DOI: 10.1074/jbc.M007364200. ISSN: 0021-9258. PMID: 11022042.
- ↑ Sundqvist, A; Sollerbrant K; Svensson C «The carboxy-terminal region of adenovirus E1A activates transcription through targeting of a C-terminal binding protein-histone deacetylase complex». FEBS Lett. [NETHERLANDS], 429, 2, Jun. 1998, pàg. 183–8. ISSN: 0014-5793. PMID: 9650586.
- ↑ Smirnov, D A; Hou S, Ricciardi R P «Association of histone deacetylase with COUP-TF in tumorigenic Ad12-transformed cells and its potential role in shut-off of MHC class I transcription». Virology [UNITED STATES], 268, 2, Mar. 2000, pàg. 319–28. DOI: 10.1006/viro.1999.0181. ISSN: 0042-6822. PMID: 10704340.
Enllaços externs
- «HDAC1» (en anglès). Medical Subject Headings.