2-Amino-3-carboxymuconic semialdehyde
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Preferred IUPAC name (2Z)-2-Amino-3-[(1Z)-3-oxoprop-1-en-1-yl]but-2-enedioic acid | |
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InChI
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Properties | |
Chemical formula | C7H7NO5 |
Molar mass | 185.13 g/mol |
Density | 1.527 g/mL |
Boiling point | 389 °C (732 °F; 662 K) |
Hazards | |
Flash point | 189 °C (372 °F; 462 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references |
Chemical compound
2-Amino-3-carboxymuconic semialdehyde[1][2] is an intermediate in the metabolism of tryptophan in the tryptophan-niacin catabolic pathway. Quinolinate is a neurotoxin formed nonenzymatically from 2-amino-3-carboxymuconic semialdehyde in mammalian tissues. 2-Amino-3-carboxymuconic semialdehyde is enzymatically converted to 2-aminomuconate via 2-aminomuconic semialdehyde.
References
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lysine→ | |
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leucine→ | |
tryptophan→alanine→ |
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G→pyruvate→ citrate |
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G→glutamate→ α-ketoglutarate |
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G→propionyl-CoA→ succinyl-CoA |
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G→fumarate |
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G→oxaloacetate |
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Cysteine metabolism |
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