OR1L3

Protein-coding gene in the species Homo sapiens
OR1L3
Identifiers
AliasesOR1L3, OR9-28, OR9-D, olfactory receptor family 1 subfamily L member 3
External IDsHomoloGene: 105279; GeneCards: OR1L3; OMA:OR1L3 - orthologs
Gene location (Human)
Chromosome 9 (human)
Chr.Chromosome 9 (human)[1]
Chromosome 9 (human)
Genomic location for OR1L3
Genomic location for OR1L3
Band9q33.2Start122,675,130 bp[1]
End122,676,104 bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • anterior cingulate cortex
    n/a
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
  • G protein-coupled receptor activity
  • signal transducer activity
  • olfactory receptor activity
Cellular component
  • integral component of membrane
  • plasma membrane
  • membrane
Biological process
  • sensory perception of smell
  • detection of chemical stimulus involved in sensory perception of smell
  • signal transduction
  • response to stimulus
  • G protein-coupled receptor signaling pathway
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

26735

n/a

Ensembl

ENSG00000171481

n/a

UniProt

Q8NH93

n/a

RefSeq (mRNA)

NM_001005234

n/a

RefSeq (protein)

NP_001005234

n/a

Location (UCSC)Chr 9: 122.68 – 122.68 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Olfactory receptor 1L3 is a protein that in humans is encoded by the OR1L3 gene.[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000171481 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ a b "Entrez Gene: OR1L3 olfactory receptor, family 1, subfamily L, member 3".

Further reading

  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
  • Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. Bibcode:2004Natur.429..369H. doi:10.1038/nature02465. PMC 2734081. PMID 15164053.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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Class I
(fish-like receptors)
Family 51
Family 52
Family 56
Class II
(tetrapod specific receptors)
Family 1
Family 2
Family 3
Family 4
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Family 9
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Family 13


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