Thyronamine
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Preferred IUPAC name 4-[4-(2-Aminoethyl)phenoxy]phenol | |
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MeSH | thyronamine |
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InChI
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Properties | |
Chemical formula | C14H15NO2 |
Molar mass | 229.279 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references |
Chemical compound
Thyronamine refers both to a molecule, and to derivatives of that molecule: a family of decarboxylated and deiodinated metabolites of the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3).
Types
The group includes:
- Thyronamine (T0AM)
- 3-Iodothyronamine (T1AM), which is the most notable one as it is a trace amine found in the nervous system. It is a possible candidate for the natural ligand of the trace amine-associated receptor TAAR1 (TAR1), an intracellular G protein-coupled receptor[1]
- 3,5-Diiodothyronamine (T2AM)
- 3,5,3'-Triiodothyronamine (T3AM)
See also
References
- ^ Piehl S, Hoefig CS, Scanlan TS, Köhrle J (2011). "Thyronamines - Past, Present, and Future". Endocrine Reviews. 32 (1): 64–80. doi:10.1210/er.2009-0040. PMID 20880963.
- v
- t
- e
- 3'-Monoiodothyronine
- 3,3'-Diiodothyronine
- 3,5-Diiodothyronine
- 3,3',5-Triiodothyronine (T3)
- 3,3',5'-Triiodothyronine (Reverse T3)
- 3,5,3',5'-Tetraiodothyronine (Thyroxine, T4)