Cefmenoxima
Cefmenoxima | ||
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Nombre (IUPAC) sistemático | ||
(6R,7R)-7-{[(2E)-2-(2-amino-1,3-thiazol-4-yl)- 2-methoxyimino-acetyl]amino}-3-[(1-methyltetrazol- 5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0] oct-2-ene-2-carboxylic acid | ||
Identificadores | ||
Número CAS | 65085-01-0 | |
Código ATC | J01DD05 | |
PubChem | 9570757 | |
DrugBank | DB00267 | |
ChemSpider | 7845223 | |
UNII | KBZ4844CXN | |
KEGG | D07641 | |
ChEBI | 55490 | |
ChEMBL | 1201224 | |
Datos químicos | ||
Fórmula | C16H17N9O5S3 | |
SMILES O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)C(=N\OC)/c3nc(sc3)N)CSc4nnnn4C)C(=O)O | ||
InChI InChI=1S/C16H17N9O5S3/c1-24-16(20-22-23-24)33-4-6-3-31-13-9(12(27)25(13)10(6)14(28)29)19-11(26)8(21-30-2)7-5-32-15(17)18-7/h5,9,13H,3-4H2,1-2H3,(H2,17,18)(H,19,26)(H,28,29)/b21-8-/t9-,13-/m1/s1 Key: HJJDBAOLQAWBMH-YCRCPZNHSA-N | ||
Farmacocinética | ||
Biodisponibilidad | 100% (dado IM) | |
Metabolismo | Despreciable | |
Vida media | 1 hora | |
Excreción | Renal, sin alterar | |
Datos clínicos | ||
Vías de adm. | Intramuscular, intravenosa | |
[editar datos en Wikidata] |
La cefmenoxima es un antibiótico cefalosporínico de tercera generación.
Enlaces externos
- «Antibacterial activities of cefmenoxime against recent fresh clinical isolates from patients in sinusitis». Jpn J Antibiot 48 (5): 602-9. 1995. PMID 7637194.
- «Pharmacoeconomic analysis of cefmenoxime dual individualization in the treatment of nosocomial pneumonia.». Ann Pharmacother 28 (3): 384-9. 1994. PMID 8193431. doi:10.1177/106002809402800316.
- «Cefmenoxime in corneal organ culture.». Ophthalmologica 208 (5): 262-6. 1994. PMID 7816419. doi:10.1159/000310505.
Datos: Q4921166