MYO5A |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/a/a8/Protein_MYO5A_PDB_1oe9.png/250px-Protein_MYO5A_PDB_1oe9.png) |
已知的結構 |
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PDB | 直系同源搜索: PDBe RCSB |
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PDBID列表 |
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4J5L、4LX1、4LX2、4LLI、4D07 |
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識別號 |
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别名 | MYO5A;, GS1, MYH12, MYO5, MYR12, myosin VA |
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外部ID | OMIM:160777 MGI:105976 HomoloGene:20100 GeneCards:MYO5A |
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基因位置(小鼠) |
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![小鼠9号染色体](//upload.wikimedia.org/wikipedia/commons/thumb/4/41/Ideogram_house_mouse_chromosome_9.svg/260px-Ideogram_house_mouse_chromosome_9.svg.png) | 染色体 | 小鼠9号染色体[2] |
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| 基因座 | 9 D|9 42.26 cM | 起始 | 74,978,297 bp[2] |
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终止 | 75,130,970 bp[2] |
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RNA表达模式 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/a/a4/PBB_GE_MYO5A_204527_at_fs.png/250px-PBB_GE_MYO5A_204527_at_fs.png) |
查阅更多表达数据 |
基因本體 |
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分子功能 | • calcium ion binding • 核苷酸結合 • calmodulin binding • microfilament motor activity • actin binding • cytoskeletal motor activity • ATP結合 • RNA binding • 无序域特异性结合 • 相同蛋白质结合 • 血浆蛋白结合 • actin filament binding
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細胞組分 | • 細胞質 • recycling endosome • 囊泡 • 细胞质基质 • 晚期内吞体 • 高尔基体 • 膜 • 生长锥 • ruffle • 黑色素体 • insulin-responsive compartment • photoreceptor outer segment • 过氧化物酶体 • secretory granule • microtubule plus-end • filopodium tip • neuronal cell body • 早期内吞体 • 内质网 • 微丝 • neuron projection • 溶酶体 • actomyosin • 中间纤维 • 外排體 • myosin complex • unconventional myosin complex • smooth endoplasmic reticulum • postsynapse • glutamatergic synapse
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生物學過程 | • regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity • melanin biosynthetic process • synapse organization • insulin secretion • secretory granule localization • melanosome localization • actin filament-based movement • post-Golgi vesicle-mediated transport • odontogenesis • endoplasmic reticulum localization • melanin metabolic process • regulation of Golgi organization • long-chain fatty acid biosynthetic process • melanosome transport • cellular response to insulin stimulus • vesicle transport along actin filament • protein transport • developmental pigmentation • 髓鞘形成 • 色素沉着 • protein localization to plasma membrane • melanocyte differentiation • locomotion involved in locomotory behavior • vesicle-mediated transport • 視覺 • 胞吐作用 • 化学性突触传递 • hair follicle maturation • transport • establishment of endoplasmic reticulum localization to postsynapse • regulation of postsynaptic cytosolic calcium ion concentration
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Sources:Amigo / QuickGO |
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直系同源 |
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物種 | 人類 | 小鼠 |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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mRNA序列 | |
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NM_000259 NM_001142495 NM_001382347 NM_001382348 NM_001382349 |
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蛋白序列 | |
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NP_000250 NP_001135967 NP_001369276 NP_001369277 NP_001369278 |
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基因位置(UCSC) | Chr 15: 52.31 – 52.53 Mb | Chr 9: 74.98 – 75.13 Mb |
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PubMed查找 | [3] | [4] |
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維基數據 |
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